168214

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3044810..3045447 Replicon chromosome
Accession NZ_CP059080
Organism Acinetobacter johnsonii strain E10B

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag H0S57_RS14720 Protein ID WP_151836024.1
Coordinates 3044810..3045196 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag H0S57_RS14725 Protein ID WP_171065375.1
Coordinates 3045202..3045447 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0S57_RS14695 3040143..3042425 - 2283 WP_151836026.1 TRAP transporter large permease subunit -
H0S57_RS14700 3042608..3043180 - 573 WP_004977887.1 rhombosortase -
H0S57_RS14705 3043252..3043815 - 564 WP_171500551.1 hypothetical protein -
H0S57_RS14710 3043812..3044054 - 243 WP_171500550.1 hypothetical protein -
H0S57_RS14715 3044509..3044733 - 225 WP_151836025.1 hypothetical protein -
H0S57_RS14720 3044810..3045196 - 387 WP_151836024.1 hypothetical protein Toxin
H0S57_RS14725 3045202..3045447 - 246 WP_171065375.1 succinate dehydrogenase assembly factor 2 Antitoxin
H0S57_RS14730 3045652..3046824 + 1173 WP_151836023.1 acyl-CoA dehydrogenase family protein -
H0S57_RS14735 3046860..3047651 - 792 WP_151836022.1 alpha/beta hydrolase -
H0S57_RS14740 3047790..3049280 - 1491 WP_151836021.1 NAD(P)/FAD-dependent oxidoreductase -
H0S57_RS14745 3049476..3049841 - 366 WP_004691290.1 50S ribosomal protein L17 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-127)

Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 15346.34 Da        Isoelectric Point: 10.6049

>T168214 WP_151836024.1 NZ_CP059080:c3045196-3044810 [Acinetobacter johnsonii]
MEHRHFQLKPSRLAYVFQLSIYAVLMLVLYQLLPLGVWLIALVAGFVLYLFFLRGPRHFQLQHLDGRDWSLSLQKQTNVQ
RVQISHIVDHRAYIVIYFQHFRAKPMLVWCDQLPITQWKSLKILTKMQ

Download         Length: 387 bp

>T168214 NZ_CP075663:c2744096-2743923 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9691.18 Da        Isoelectric Point: 5.1473

>AT168214 WP_171065375.1 NZ_CP059080:c3045447-3045202 [Acinetobacter johnsonii]
MSLEERKVIYRARRGLKEIDVYFDPYVKNYYLQADPAEKAMFAALVEQEDPDLLDWFMEVSEPPRPEMKTLIQKLKHYVH
G

Download         Length: 246 bp

>AT168214 NZ_CP075663:c2744420-2744124 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References