Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3576064..3576705 Replicon chromosome
Accession NZ_CP059078
Organism Acinetobacter nosocomialis strain WM98B

Toxin (Protein)


Gene name cptA Uniprot ID A0A7S8XRH8
Locus tag H0S59_RS16705 Protein ID WP_025466887.1
Coordinates 3576064..3576453 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag H0S59_RS16710 Protein ID WP_151276929.1
Coordinates 3576460..3576705 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0S59_RS16690 3571178..3573373 - 2196 WP_006582604.1 TRAP transporter large permease subunit -
H0S59_RS16695 3573561..3574127 - 567 WP_004711824.1 rhombosortase -
H0S59_RS16700 3574211..3575296 - 1086 WP_002049690.1 hypothetical protein -
H0S59_RS16705 3576064..3576453 - 390 WP_025466887.1 hypothetical protein Toxin
H0S59_RS16710 3576460..3576705 - 246 WP_151276929.1 succinate dehydrogenase assembly factor 2 Antitoxin
H0S59_RS16715 3576907..3578079 + 1173 WP_002049748.1 acyl-CoA dehydrogenase family protein -
H0S59_RS16720 3578128..3579618 - 1491 WP_006582603.1 NAD(P)/FAD-dependent oxidoreductase -
H0S59_RS16725 3579800..3580177 - 378 WP_002049717.1 50S ribosomal protein L17 -
H0S59_RS16730 3580196..3581203 - 1008 WP_002049752.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15624.70 Da        Isoelectric Point: 10.0990

>T168213 WP_025466887.1 NZ_CP059078:c3576453-3576064 [Acinetobacter nosocomialis]
MVNHLNFKLKYSRFAIIFQFFIGLSLVVLFYQLLPILWWLVTVSLLFISFIFFLKRPQLAQIAHLDQKLWSLSFHSEQTI
SRVEILKIIDYQIFIVVYFEGHKTLTSVIWFDQMPLSQWKQLKTLEKFY

Download         Length: 390 bp

>T168213 NZ_CP075663:2199908-2200186 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAAGTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9802.20 Da        Isoelectric Point: 5.1802

>AT168213 WP_151276929.1 NZ_CP059078:c3576705-3576460 [Acinetobacter nosocomialis]
MTLEERKVVYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIHKLKHYVH
G

Download         Length: 246 bp

>AT168213 NZ_CP075663:2199645-2199905 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References