Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1192518..1193028 Replicon chromosome
Accession NZ_CP059078
Organism Acinetobacter nosocomialis strain WM98B

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag H0S59_RS05675 Protein ID WP_111936989.1
Coordinates 1192518..1192781 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7S8XU62
Locus tag H0S59_RS05680 Protein ID WP_001165438.1
Coordinates 1192765..1193028 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0S59_RS05665 1189596..1190804 + 1209 WP_033854479.1 integrase arm-type DNA-binding domain-containing protein -
H0S59_RS05670 1190912..1192285 + 1374 WP_033847035.1 hypothetical protein -
H0S59_RS05675 1192518..1192781 - 264 WP_111936989.1 Txe/YoeB family addiction module toxin Toxin
H0S59_RS05680 1192765..1193028 - 264 WP_001165438.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
H0S59_RS05685 1193375..1193641 - 267 WP_111936990.1 AlpA family phage regulatory protein -
H0S59_RS05690 1193662..1193952 - 291 WP_111936991.1 pyocin activator PrtN family protein -
H0S59_RS05695 1194151..1195128 + 978 WP_111936992.1 hypothetical protein -
H0S59_RS05700 1195392..1196126 - 735 WP_033847037.1 hypothetical protein -
H0S59_RS05705 1196211..1196855 - 645 WP_033847038.1 DUF805 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10335.94 Da        Isoelectric Point: 9.0098

>T168211 WP_111936989.1 NZ_CP059078:c1192781-1192518 [Acinetobacter nosocomialis]
MKRKTSFTPIAWEDYVYWQNQDKKTLKRINTLIKECLRTPFDGIGKPEPLLGDLAGLWSRRIDEKNRLVYEVTDVAITVI
SCRYHYE

Download         Length: 264 bp

>T168211 NZ_CP075663:1990695-1990913 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9796.01 Da        Isoelectric Point: 4.6112

>AT168211 WP_001165438.1 NZ_CP059078:c1193028-1192765 [Acinetobacter nosocomialis]
MQIFTYTDARNNLKTVLDRVIDDSDVAVITRKEGQHAVVMGQDYYNSIMETLHLMSSPSNAAHLAKSIAELRASKAIERE
LLDETED

Download         Length: 264 bp

>AT168211 NZ_CP075663:1990295-1990669 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References