Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2380054..2380868 Replicon chromosome
Accession NZ_CP059068
Organism Rhodoferax sp. AJA081-3

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag HZ993_RS11095 Protein ID WP_209397914.1
Coordinates 2380054..2380554 (-) Length 167 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag HZ993_RS11100 Protein ID WP_209397916.1
Coordinates 2380551..2380868 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZ993_RS11080 (HZ993_11080) 2375521..2377539 + 2019 WP_209397908.1 flagellar hook-associated protein FlgK -
HZ993_RS11085 (HZ993_11085) 2377565..2378833 + 1269 WP_209397910.1 flagellar hook-associated protein FlgL -
HZ993_RS11090 (HZ993_11090) 2378861..2380057 + 1197 WP_209397912.1 HDOD domain-containing protein -
HZ993_RS11095 (HZ993_11095) 2380054..2380554 - 501 WP_209397914.1 GNAT family N-acetyltransferase Toxin
HZ993_RS11100 (HZ993_11100) 2380551..2380868 - 318 WP_209397916.1 DUF1778 domain-containing protein Antitoxin
HZ993_RS11105 (HZ993_11105) 2380953..2382386 - 1434 WP_209397918.1 PLP-dependent aminotransferase family protein -
HZ993_RS11110 (HZ993_11110) 2382532..2383143 + 612 WP_209397920.1 LysE family translocator -
HZ993_RS11115 (HZ993_11115) 2383140..2384084 + 945 WP_245213910.1 DMT family transporter -
HZ993_RS11120 (HZ993_11120) 2384408..2385613 + 1206 WP_209397922.1 PLP-dependent aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

Vibrio phage ICP1, Orf50

(22-98)


Sequences

Toxin        


Download         Length: 167 a.a.        Molecular weight: 18234.08 Da        Isoelectric Point: 9.5438

>T168208 WP_209397914.1 NZ_CP059068:c2380554-2380054 [Rhodoferax sp. AJA081-3]
MTFGAPVPLQALHRLDSFDCGKPSLNEWLTRYARQSQASGSAKTFVVAHDDGVVGYFSLTVGQVDTLEAPERIRKGMGQY
PVPVVILARLAVAQQAQGHGVGIGMLQDAIRRTLLIAEQAGIRALLTHPLDADAARFYLRFGFEASPLRPDQLLLLLKDA
RRWVQV

Download         Length: 501 bp

>T168208 NZ_CP075663:977892-977999 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11457.99 Da        Isoelectric Point: 7.2782

>AT168208 WP_209397916.1 NZ_CP059068:c2380868-2380551 [Rhodoferax sp. AJA081-3]
MTSAVAPHTPSARSANAARSARLGLRATDQQEAILRRAAEVAHKSLTDFILDSACLAAEQTLLDQRLFMVSGSQYQALMD
LLDRPAQDNPGLKDLFSHKAPWDKP

Download         Length: 318 bp

>AT168208 NZ_CP075663:c977842-977779 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References