Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapB(antitoxin)
Location 1493038..1493624 Replicon chromosome
Accession NZ_CP059068
Organism Rhodoferax sp. AJA081-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HZ993_RS06915 Protein ID WP_209396511.1
Coordinates 1493241..1493624 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HZ993_RS06910 Protein ID WP_209396510.1
Coordinates 1493038..1493244 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZ993_RS06895 (HZ993_06900) 1488089..1490329 + 2241 WP_209396507.1 molybdopterin-dependent oxidoreductase -
HZ993_RS06900 (HZ993_06905) 1491023..1492192 + 1170 WP_209396508.1 hypothetical protein -
HZ993_RS06905 (HZ993_06910) 1492354..1492761 - 408 WP_209396509.1 transcriptional regulator -
HZ993_RS06910 (HZ993_06915) 1493038..1493244 + 207 WP_209396510.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
HZ993_RS06915 (HZ993_06920) 1493241..1493624 + 384 WP_209396511.1 PIN domain-containing protein Toxin
HZ993_RS06920 (HZ993_06925) 1493605..1494246 - 642 WP_209396512.1 TetR family transcriptional regulator -
HZ993_RS06925 (HZ993_06930) 1494419..1495696 + 1278 WP_209396513.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14097.30 Da        Isoelectric Point: 6.2188

>T168206 WP_209396511.1 NZ_CP059068:1493241-1493624 [Rhodoferax sp. AJA081-3]
MSVLIDTSVWCDHFRRRNGVLAELIQLDQALTHPLVVGELACGTPPEPRVRTLGDIELLQAANQASVDEVRAFIEREKLY
GLGCGWVDFSLLASTLITPGARLWTLDKRLAELAVRFGRSFITPSVH

Download         Length: 384 bp

>T168206 NZ_CP075663:976821-976928 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7581.76 Da        Isoelectric Point: 6.2837

>AT168206 WP_209396510.1 NZ_CP059068:1493038-1493244 [Rhodoferax sp. AJA081-3]
MRTTVTIEDALYEKALEVADPTMEKSEIFREAMKTFVRVQAAKRLAALGGTLPNMQDIPRRGSDITTP

Download         Length: 207 bp

>AT168206 NZ_CP075663:c976774-976708 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References