168195

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 19188..19881 Replicon plasmid pBS1142
Accession NZ_CP059054
Organism Pseudomonas putida strain BS3701

Toxin (Protein)


Gene name tad Uniprot ID N2IHR9
Locus tag H0H12_RS29640 Protein ID WP_003151133.1
Coordinates 19188..19565 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID N2IIN5
Locus tag H0H12_RS29645 Protein ID WP_001172026.1
Coordinates 19546..19881 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0H12_RS29630 15381..18410 - 3030 WP_010799689.1 Tn3 family transposase -
H0H12_RS29635 18394..18996 - 603 WP_010465829.1 recombinase family protein -
H0H12_RS29640 19188..19565 + 378 WP_003151133.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H0H12_RS29645 19546..19881 + 336 WP_001172026.1 helix-turn-helix domain-containing protein Antitoxin
H0H12_RS29650 19896..20231 + 336 WP_000741275.1 hypothetical protein -
H0H12_RS29655 20255..20581 + 327 WP_000091614.1 hypothetical protein -
H0H12_RS29660 20578..20949 + 372 WP_023294894.1 hypothetical protein -
H0H12_RS29665 21241..21444 - 204 WP_180690221.1 hypothetical protein -
H0H12_RS29670 22228..22368 + 141 WP_180690222.1 hypothetical protein -
H0H12_RS29675 22519..22791 + 273 WP_180690223.1 hypothetical protein -
H0H12_RS29680 22796..23368 + 573 WP_180690224.1 recombinase family protein -
H0H12_RS29685 23379..23717 + 339 WP_180690225.1 hypothetical protein -
H0H12_RS29690 23721..24140 + 420 WP_180690226.1 hypothetical protein -
H0H12_RS29695 24289..24447 - 159 WP_180690227.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..54501 54501


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 16167.95 Da        Isoelectric Point: 12.8969

>T168195 WP_003151133.1 NZ_CP059054:19188-19565 [Pseudomonas putida]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 378 bp

>T168195 NZ_CP075652:4565184-4565438 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 14373.51 Da        Isoelectric Point: 12.8453

>AT168195 WP_001172026.1 NZ_CP059054:19546-19881 [Pseudomonas putida]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 336 bp

>AT168195 NZ_CP075652:4564936-4565187 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A024ELN5

Antitoxin

Source ID Structure
AlphaFold DB A0A024EKI7

References