Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 9035..9566 Replicon plasmid pBS1142
Accession NZ_CP059054
Organism Pseudomonas putida strain BS3701

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H0H12_RS29600 Protein ID WP_180690175.1
Coordinates 9285..9566 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag H0H12_RS29595 Protein ID WP_180690176.1
Coordinates 9035..9298 (+) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0H12_RS29565 4478..6139 - 1662 WP_180690178.1 DDE-type integrase/transposase/recombinase -
H0H12_RS29570 6120..6695 - 576 WP_180690177.1 recombinase family protein -
H0H12_RS29575 6824..7390 - 567 WP_003159185.1 recombinase family protein -
H0H12_RS29580 7572..7823 + 252 WP_003108276.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
H0H12_RS29585 7820..8215 + 396 WP_003159186.1 type II toxin-antitoxin system VapC family toxin -
H0H12_RS29590 8221..8556 + 336 Protein_12 transposase -
H0H12_RS29595 9035..9298 + 264 WP_180690176.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H0H12_RS29600 9285..9566 + 282 WP_180690175.1 type II toxin-antitoxin system YafQ family toxin Toxin
H0H12_RS29605 9603..9787 + 185 Protein_15 hypothetical protein -
H0H12_RS29610 9787..10035 + 249 Protein_16 hypothetical protein -
H0H12_RS29615 10125..11750 - 1626 WP_180690174.1 methyl-accepting chemotaxis protein -
H0H12_RS29620 12053..12910 - 858 WP_180690173.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..54501 54501


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-73)

Antitoxin

(5-84)


Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T168194 WP_180690175.1 NZ_CP059054:9285-9566 [Pseudomonas putida]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T168194 NZ_CP075652:4564936-4565187 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 11297.34 Da        Isoelectric Point: 12.7395

>AT168194 WP_180690176.1 NZ_CP059054:9035-9298 [Pseudomonas putida]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKK

Download         Length: 264 bp

>AT168194 NZ_CP075652:4565184-4565438 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References