Detailed information of TA system TA168193

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 86701..87232
• Replicon: plasmid pBS1141
• Accession: NZ_CP059053
• Organism: Pseudomonas putida strain BS3701

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: H0H12_RS29405
• Protein ID: WP_180690175.1
• Coordinates: 86701..86982 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: H0H12_RS29410
• Protein ID: WP_180690176.1
• Coordinates: 86969..87232 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H0H12_RS29385	83357..84214	+	858	WP_180690173.1	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	-
H0H12_RS29390	84517..86142	+	1626	WP_180690174.1	methyl-accepting chemotaxis protein	-
H0H12_RS29395	86232..86480	-	249	Protein_103	hypothetical protein	-
H0H12_RS29400	86480..86664	-	185	Protein_104	hypothetical protein	-
H0H12_RS29405	86701..86982	-	282	WP_180690175.1	type II toxin-antitoxin system YafQ family toxin	Toxin
H0H12_RS29410	86969..87232	-	264	WP_180690176.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
H0H12_RS29415	87711..88046	-	336	Protein_107	transposase	-
H0H12_RS29420	88052..88447	-	396	WP_003159186.1	type II toxin-antitoxin system VapC family toxin	-
H0H12_RS29425	88444..88695	-	252	WP_003108276.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
H0H12_RS29430	88877..89443	+	567	WP_003159185.1	recombinase family protein	-
H0H12_RS29435	89572..90147	+	576	WP_180690177.1	recombinase family protein	-
H0H12_RS29440	90128..91789	+	1662	WP_180690178.1	DDE-type integrase/transposase/recombinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..107388	107388

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-125)

Antitoxin

• SpoVT-AbrB domain (7-52)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 13852.62 Da
• Isoelectric Point: 5.5500

>T168193 WP_180690175.1 NZ_CP059053:c86982-86701 [Pseudomonas putida]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Nucleotide

• Length: 282 bp

>T168193 NZ_CP075652:4095179-4095577 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 12969.56 Da
• Isoelectric Point: 5.5500

>AT168193 WP_180690176.1 NZ_CP059053:c87232-86969 [Pseudomonas putida]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFF

Nucleotide

• Length: 264 bp

>AT168193 NZ_CP075652:4094952-4095179 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA