Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 86701..87232 Replicon plasmid pBS1141
Accession NZ_CP059053
Organism Pseudomonas putida strain BS3701

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H0H12_RS29405 Protein ID WP_180690175.1
Coordinates 86701..86982 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag H0H12_RS29410 Protein ID WP_180690176.1
Coordinates 86969..87232 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0H12_RS29385 83357..84214 + 858 WP_180690173.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -
H0H12_RS29390 84517..86142 + 1626 WP_180690174.1 methyl-accepting chemotaxis protein -
H0H12_RS29395 86232..86480 - 249 Protein_103 hypothetical protein -
H0H12_RS29400 86480..86664 - 185 Protein_104 hypothetical protein -
H0H12_RS29405 86701..86982 - 282 WP_180690175.1 type II toxin-antitoxin system YafQ family toxin Toxin
H0H12_RS29410 86969..87232 - 264 WP_180690176.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H0H12_RS29415 87711..88046 - 336 Protein_107 transposase -
H0H12_RS29420 88052..88447 - 396 WP_003159186.1 type II toxin-antitoxin system VapC family toxin -
H0H12_RS29425 88444..88695 - 252 WP_003108276.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
H0H12_RS29430 88877..89443 + 567 WP_003159185.1 recombinase family protein -
H0H12_RS29435 89572..90147 + 576 WP_180690177.1 recombinase family protein -
H0H12_RS29440 90128..91789 + 1662 WP_180690178.1 DDE-type integrase/transposase/recombinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..107388 107388


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T168193 WP_180690175.1 NZ_CP059053:c86982-86701 [Pseudomonas putida]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T168193 NZ_CP075652:4095179-4095577 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 12969.56 Da        Isoelectric Point: 5.5500

>AT168193 WP_180690176.1 NZ_CP059053:c87232-86969 [Pseudomonas putida]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFF

Download         Length: 264 bp

>AT168193 NZ_CP075652:4094952-4095179 [Escherichia coli]
ATGGAAACTACTGTATTTTTAAGTAATCGCAGTCAGGCCGTCAGATTACCGAAAGCGGTCGCTCTGCCAGAAGACGTTAA
GAAAGTAGAAATTATTGCGATTGGTCGTACAAGAATCATCACTCCCGCCGGTGAGTCCTGGGACAGTTGGTTTGATGGCG
AAAATGTGAGTGCGGATTTTATGGATATCCGTGATCAACCCGCAATGCAGGAAAGGGAATCATTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References