168192

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 76386..77079 Replicon plasmid pBS1141
Accession NZ_CP059053
Organism Pseudomonas putida strain BS3701

Toxin (Protein)


Gene name tad Uniprot ID N2IHR9
Locus tag H0H12_RS29365 Protein ID WP_003151133.1
Coordinates 76702..77079 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID N2IIN5
Locus tag H0H12_RS29360 Protein ID WP_001172026.1
Coordinates 76386..76721 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0H12_RS29325 72209..73132 - 924 WP_011117431.1 catechol 2,3-dioxygenase -
H0H12_RS29330 73153..73470 - 318 WP_180690171.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
H0H12_RS29335 73454..73672 - 219 WP_024265233.1 hypothetical protein -
H0H12_RS29340 73970..75274 - 1305 WP_011154425.1 salicylate 1-monooxygenase -
H0H12_RS29345 75318..75689 - 372 WP_023294894.1 hypothetical protein -
H0H12_RS29350 75686..76012 - 327 WP_000091614.1 hypothetical protein -
H0H12_RS29355 76036..76371 - 336 WP_000741275.1 hypothetical protein -
H0H12_RS29360 76386..76721 - 336 WP_001172026.1 helix-turn-helix domain-containing protein Antitoxin
H0H12_RS29365 76702..77079 - 378 WP_003151133.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H0H12_RS29370 77271..77873 + 603 WP_010465829.1 recombinase family protein -
H0H12_RS29375 77857..80886 + 3030 WP_010799689.1 Tn3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..107388 107388


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-109)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 18562.27 Da        Isoelectric Point: 5.5500

>T168192 WP_003151133.1 NZ_CP059053:c77079-76702 [Pseudomonas putida]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 378 bp

>T168192 NZ_CP075652:3800325-3800660 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 16501.79 Da        Isoelectric Point: 5.5500

>AT168192 WP_001172026.1 NZ_CP059053:c76721-76386 [Pseudomonas putida]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 336 bp

>AT168192 NZ_CP075652:3800077-3800325 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A024ELN5

Antitoxin

Source ID Structure
AlphaFold DB A0A024EKI7

References