Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3453935..3454598 Replicon chromosome
Accession NZ_CP059045
Organism Cronobacter sakazakii strain 5563_17

Toxin (Protein)


Gene name cptA Uniprot ID A0A6L3S892
Locus tag HZZ03_RS16090 Protein ID WP_012123856.1
Coordinates 3453935..3454351 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A3Q9CFW7
Locus tag HZZ03_RS16095 Protein ID WP_007870701.1
Coordinates 3454332..3454598 (-) Length 89 a.a.

Genomic Context


HZZ03_RS16085HZZ03_RS16100HZZ03_RS16115HZZ03_RS16120HZZ03_RS16070HZZ03_RS16075HZZ03_RS16080HZZ03_RS16090HZZ03_RS16095HZZ03_RS16105HZZ03_RS16110
Location: 3453400..3453921 (522 bp)
Type: Others
Protein ID: WP_004385676.1
Location: 3454876..3455865 (990 bp)
Type: Others
Protein ID: WP_007870703.1
Location: 3457257..3457985 (729 bp)
Type: Others
Protein ID: WP_180552886.1
Location: 3458137..3459570 (1434 bp)
Type: Others
Protein ID: WP_012123851.1
Location: 3449923..3451656 (1734 bp)
Type: Others
Protein ID: WP_041460381.1
Location: 3451660..3452379 (720 bp)
Type: Others
Protein ID: WP_004385678.1
Location: 3452402..3453298 (897 bp)
Type: Others
Protein ID: WP_004385677.1
Location: 3453935..3454351 (417 bp)
Type: Toxin
Protein ID: WP_012123856.1
Location: 3454332..3454598 (267 bp)
Type: Antitoxin
Protein ID: WP_007870701.1
Location: 3455970..3456623 (654 bp)
Type: Others
Protein ID: WP_007777939.1
Location: 3456766..3457080 (315 bp)
Type: Others
Protein ID: WP_012123853.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HZZ03_RS160703449923..3451656-1734WP_041460381.1single-stranded-DNA-specific exonuclease RecJ-
HZZ03_RS160753451660..3452379-720WP_004385678.1bifunctional protein-disulfide isomerase/oxidoreductase DsbC-
HZZ03_RS160803452402..3453298-897WP_004385677.1site-specific tyrosine recombinase XerD-
HZZ03_RS160853453400..3453921+522WP_004385676.1flavodoxin FldB-
HZZ03_RS160903453935..3454351-417WP_012123856.1protein YgfXToxin
HZZ03_RS160953454332..3454598-267WP_007870701.1FAD assembly factor SdhEAntitoxin
HZZ03_RS161003454876..3455865+990WP_007870703.1tRNA-modifying protein YgfZ-
HZZ03_RS161053455970..3456623-654WP_007777939.1hemolysin III family protein-
HZZ03_RS161103456766..3457080-315WP_012123853.1N(4)-acetylcytidine aminohydrolase-
HZZ03_RS161153457257..3457985+729WP_180552886.1MurR/RpiR family transcriptional regulator-
HZZ03_RS161203458137..3459570+1434WP_012123851.16-phospho-beta-glucosidase-

Associated MGEs


Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-132)

Antitoxin

(7-79)


Sequences


Toxin        


Download         Length: 139 a.a.        Molecular weight: 16467.47 Da        Isoelectric Point: 11.2099

>T168172 WP_012123856.1 NZ_CP059045:c3454351-3453935 [Cronobacter sakazakii]
VVLWHSDLRVSWRSQWLSLLLHGAVAVIILLLPWPLRYLPVWMLLLSLVVFDCVRSQRRINAFQGEVSLTADYYLRWQGV
DWQICATPWMLRSGMMLRLRHPKTTRRHHVWLAADSMTEAEWRDLRRLLLQQPVGDKR

Download         Length: 417 bp

>T168172 NZ_CP075649:c4680339-4680166 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10411.89 Da        Isoelectric Point: 4.8310

>AT168172 WP_007870701.1 NZ_CP059045:c3454598-3454332 [Cronobacter sakazakii]
MDINNKARIHWACRRGMRELDISIMPFFEYDYDSLSDEDKRVFVRLLECDDPDLFNWLMNHGKPADAELARMVELIQQRN
QARGPVAL

Download         Length: 267 bp

>AT168172 NZ_CP075649:c4680663-4680367 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins


Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A6L3S892


Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A3Q9CFW7

References