Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 3453935..3454598 | Replicon | chromosome |
Accession | NZ_CP059045 | ||
Organism | Cronobacter sakazakii strain 5563_17 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A6L3S892 |
Locus tag | HZZ03_RS16090 | Protein ID | WP_012123856.1 |
Coordinates | 3453935..3454351 (-) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A3Q9CFW7 |
Locus tag | HZZ03_RS16095 | Protein ID | WP_007870701.1 |
Coordinates | 3454332..3454598 (-) | Length | 89 a.a. |
Genomic Context
Location: 3453400..3453921 (522 bp)
Type: Others
Protein ID: WP_004385676.1
Type: Others
Protein ID: WP_004385676.1
Location: 3454876..3455865 (990 bp)
Type: Others
Protein ID: WP_007870703.1
Type: Others
Protein ID: WP_007870703.1
Location: 3457257..3457985 (729 bp)
Type: Others
Protein ID: WP_180552886.1
Type: Others
Protein ID: WP_180552886.1
Location: 3458137..3459570 (1434 bp)
Type: Others
Protein ID: WP_012123851.1
Type: Others
Protein ID: WP_012123851.1
Location: 3449923..3451656 (1734 bp)
Type: Others
Protein ID: WP_041460381.1
Type: Others
Protein ID: WP_041460381.1
Location: 3451660..3452379 (720 bp)
Type: Others
Protein ID: WP_004385678.1
Type: Others
Protein ID: WP_004385678.1
Location: 3452402..3453298 (897 bp)
Type: Others
Protein ID: WP_004385677.1
Type: Others
Protein ID: WP_004385677.1
Location: 3453935..3454351 (417 bp)
Type: Toxin
Protein ID: WP_012123856.1
Type: Toxin
Protein ID: WP_012123856.1
Location: 3454332..3454598 (267 bp)
Type: Antitoxin
Protein ID: WP_007870701.1
Type: Antitoxin
Protein ID: WP_007870701.1
Location: 3455970..3456623 (654 bp)
Type: Others
Protein ID: WP_007777939.1
Type: Others
Protein ID: WP_007777939.1
Location: 3456766..3457080 (315 bp)
Type: Others
Protein ID: WP_012123853.1
Type: Others
Protein ID: WP_012123853.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HZZ03_RS16070 | 3449923..3451656 | - | 1734 | WP_041460381.1 | single-stranded-DNA-specific exonuclease RecJ | - |
HZZ03_RS16075 | 3451660..3452379 | - | 720 | WP_004385678.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
HZZ03_RS16080 | 3452402..3453298 | - | 897 | WP_004385677.1 | site-specific tyrosine recombinase XerD | - |
HZZ03_RS16085 | 3453400..3453921 | + | 522 | WP_004385676.1 | flavodoxin FldB | - |
HZZ03_RS16090 | 3453935..3454351 | - | 417 | WP_012123856.1 | protein YgfX | Toxin |
HZZ03_RS16095 | 3454332..3454598 | - | 267 | WP_007870701.1 | FAD assembly factor SdhE | Antitoxin |
HZZ03_RS16100 | 3454876..3455865 | + | 990 | WP_007870703.1 | tRNA-modifying protein YgfZ | - |
HZZ03_RS16105 | 3455970..3456623 | - | 654 | WP_007777939.1 | hemolysin III family protein | - |
HZZ03_RS16110 | 3456766..3457080 | - | 315 | WP_012123853.1 | N(4)-acetylcytidine aminohydrolase | - |
HZZ03_RS16115 | 3457257..3457985 | + | 729 | WP_180552886.1 | MurR/RpiR family transcriptional regulator | - |
HZZ03_RS16120 | 3458137..3459570 | + | 1434 | WP_012123851.1 | 6-phospho-beta-glucosidase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 16467.47 Da Isoelectric Point: 11.2099
>T168172 WP_012123856.1 NZ_CP059045:c3454351-3453935 [Cronobacter sakazakii]
VVLWHSDLRVSWRSQWLSLLLHGAVAVIILLLPWPLRYLPVWMLLLSLVVFDCVRSQRRINAFQGEVSLTADYYLRWQGV
DWQICATPWMLRSGMMLRLRHPKTTRRHHVWLAADSMTEAEWRDLRRLLLQQPVGDKR
VVLWHSDLRVSWRSQWLSLLLHGAVAVIILLLPWPLRYLPVWMLLLSLVVFDCVRSQRRINAFQGEVSLTADYYLRWQGV
DWQICATPWMLRSGMMLRLRHPKTTRRHHVWLAADSMTEAEWRDLRRLLLQQPVGDKR
Download Length: 417 bp
>T168172 NZ_CP075649:c4680339-4680166 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10411.89 Da Isoelectric Point: 4.8310
>AT168172 WP_007870701.1 NZ_CP059045:c3454598-3454332 [Cronobacter sakazakii]
MDINNKARIHWACRRGMRELDISIMPFFEYDYDSLSDEDKRVFVRLLECDDPDLFNWLMNHGKPADAELARMVELIQQRN
QARGPVAL
MDINNKARIHWACRRGMRELDISIMPFFEYDYDSLSDEDKRVFVRLLECDDPDLFNWLMNHGKPADAELARMVELIQQRN
QARGPVAL
Download Length: 267 bp
>AT168172 NZ_CP075649:c4680663-4680367 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6L3S892 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3Q9CFW7 |