Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1951563..1951834 Replicon chromosome
Accession NZ_CP059003
Organism Escherichia coli strain 2D

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1951694..1951796 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1951563..1951834 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0E72_RS09340 1948118..1948780 - 663 WP_000944256.1 exodeoxyribonuclease X -
H0E72_RS09345 1948804..1949460 - 657 WP_000011663.1 carbon-nitrogen hydrolase family protein -
H0E72_RS09350 1949562..1949792 - 231 WP_024176156.1 DNA polymerase III subunit theta -
H0E72_RS09355 1949931..1950305 + 375 WP_000168737.1 CopC domain-containing protein YobA -
H0E72_RS09360 1950309..1951181 + 873 WP_000879322.1 copper homeostasis membrane protein CopD -
H0E72_RS09365 1951194..1951535 + 342 WP_000976474.1 YebY family protein -
- 1951563..1951834 - 272 - - Antitoxin
- 1951694..1951796 + 103 - - Toxin
H0E72_RS09370 1951931..1952587 + 657 WP_000812749.1 protein-serine/threonine phosphatase -
H0E72_RS09375 1952588..1952779 - 192 WP_001296140.1 YebW family protein -
H0E72_RS09380 1952884..1953120 - 237 WP_001295499.1 DUF1480 family protein -
H0E72_RS09385 1953238..1954677 - 1440 WP_024175799.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T168080 NZ_CP059003:1951694-1951796 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT168080 NZ_CP059003:c1951834-1951563 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGATTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References