Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 856415..857094 Replicon chromosome
Accession NZ_CP058970
Organism Delftia acidovorans strain B804

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag H0G62_RS03845 Protein ID WP_180318716.1
Coordinates 856669..857094 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag H0G62_RS03840 Protein ID WP_180318715.1
Coordinates 856415..856672 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0G62_RS03815 852156..852950 - 795 WP_180318710.1 cobalt-precorrin-6A reductase -
H0G62_RS03820 852949..854151 + 1203 WP_180318711.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
H0G62_RS03825 854148..854645 + 498 WP_180318712.1 cobalamin biosynthesis protein -
H0G62_RS03830 854642..855496 + 855 WP_180318713.1 precorrin-4 C(11)-methyltransferase -
H0G62_RS03835 855493..856311 + 819 WP_180318714.1 precorrin-6A synthase (deacetylating) -
H0G62_RS03840 856415..856672 + 258 WP_180318715.1 plasmid stability protein stbC Antitoxin
H0G62_RS03845 856669..857094 + 426 WP_180318716.1 type II toxin-antitoxin system VapC family toxin Toxin
H0G62_RS03850 857133..858182 - 1050 WP_180318717.1 NAD(P)-dependent alcohol dehydrogenase -
H0G62_RS03855 858324..859217 + 894 WP_013800520.1 LysR family transcriptional regulator -
H0G62_RS03860 859375..860862 + 1488 WP_180318718.1 chloride channel protein -
H0G62_RS03865 860978..861490 + 513 WP_012207634.1 MgtC/SapB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15222.47 Da        Isoelectric Point: 5.6390

>T168061 WP_180318716.1 NZ_CP058970:856669-857094 [Delftia acidovorans]
MIVVDTNVISELWRLAPDSRVLAWMDAQAIETLHLSAVTVAELRYGIAAMPEGRRRTIYQERLEHEVLPAFAGRVLAFDL
DAAKAYADLMASAKTQGRAIAKADGYIAATAMAHGLVVATRDTSPFEAGGLQTINPWTAAP

Download         Length: 426 bp

>T168061 NZ_CP075605:56842-57237 [Enterococcus faecalis]
ATGGCGAATATTACTGACTTCACCGAAAAGCAATTTGAAGATCGTTTAGAAAAGAATGTTGAACGACTAACTAAAAATAG
ACTAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCAAATTTTGACGAATTAGTG
AAACTCTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCGAATCGCATGACAGAAGCACTTATTAGCCGTTTAAG
CGATCAAGGCTATAATTTAGTGATTGAAGGGTTCTGTTGCAAAGTTTTAAATCTACTATCAAATAAGGTAGAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9345.53 Da        Isoelectric Point: 6.7279

>AT168061 WP_180318715.1 NZ_CP058970:856415-856672 [Delftia acidovorans]
MANVTVRNLPDAVHRALRVRAAHHGRSTEAEIRDILEAAVRPAERVRLGSMLASIAREAGGLTDSEAEGFNRLRDRAPAE
PMDFE

Download         Length: 258 bp

>AT168061 NZ_CP075605:56568-56840 [Enterococcus faecalis]
ATGGCAGTTACGTATGAAAAAACATTTGAAATTGAAATCATTAATGAGTTATCGGCAAGTGTTTATAATCGGGTATTAAA
TTATGTTTTGAATCATGAACTAGATACTAAAAATACTCGTTTACTAGAAGTGAATCTTTTAAATCAATTAGAAGTGGCAC
AAGAAGTTGATTTATTTCAACAACCATTTGAAGAATTACAAGCTATTCATGAGTATTGGCGGTCAATGAATCAATATTCA
AAACAAATTTTGAATAAAGAGAAAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References