Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3726281..3726426 Replicon chromosome
Accession NZ_CP058940
Organism Klebsiella pneumoniae strain BA39649

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3726317..3726419 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3726281..3726426 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBJ39_RS18150 3721411..3723471 + 2061 WP_004151449.1 oligopeptidase B -
HBJ39_RS18155 3723475..3724134 - 660 WP_002911407.1 exodeoxyribonuclease X -
HBJ39_RS18160 3724213..3724443 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HBJ39_RS18165 3724556..3724930 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HBJ39_RS18170 3724934..3725803 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
HBJ39_RS18175 3725820..3726158 + 339 WP_009307539.1 YebY family protein -
- 3726281..3726426 - 146 - - Antitoxin
- 3726317..3726419 + 103 - - Toxin
HBJ39_RS18180 3726795..3726938 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HBJ39_RS18185 3727043..3728018 - 976 Protein_3527 VirK/YbjX family protein -
HBJ39_RS18190 3728175..3728828 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
HBJ39_RS18195 3728825..3729016 - 192 WP_002911395.1 YebW family protein -
HBJ39_RS18200 3729114..3729353 - 240 WP_002911393.1 YebV family protein -
HBJ39_RS18205 3729469..3730902 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T167968 NZ_CP058940:3726317-3726419 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT167968 NZ_CP058940:c3726426-3726281 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References