Detailed information of TA system TA167956

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 3842672..3843303
• Replicon: chromosome
• Accession: NZ_CP058907
• Organism: Rhodopseudomonas palustris strain CGMCC 1.2180

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: HZF03_RS17555
• Protein ID: WP_119017242.1
• Coordinates: 3842672..3843076 (-)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: HZF03_RS17560
• Protein ID: WP_119017290.1
• Coordinates: 3843073..3843303 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HZF03_RS17540	3837686..3837928	-	243	WP_119017240.1	hypothetical protein	-
HZF03_RS17545	3838266..3839489	+	1224	WP_119017241.1	efflux RND transporter periplasmic adaptor subunit	-
HZF03_RS17550	3839492..3842629	+	3138	WP_011159023.1	multidrug efflux RND transporter permease subunit	-
HZF03_RS17555	3842672..3843076	-	405	WP_119017242.1	PIN domain-containing protein	Toxin
HZF03_RS17560	3843073..3843303	-	231	WP_119017290.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
HZF03_RS17570	3843900..3845093	-	1194	WP_119017243.1	CoA transferase	-
HZF03_RS17575	3845203..3846414	-	1212	WP_119017244.1	ABC transporter substrate-binding protein	-
HZF03_RS17580	3846663..3847277	-	615	WP_119017245.1	class I SAM-dependent methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-115)

Antitoxin

• SpoVT-AbrB domain (5-44)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 14844.74 Da
• Isoelectric Point: 5.1484

>T167956 WP_119017242.1 NZ_CP058907:c3843076-3842672 [Rhodopseudomonas palustris]
VRAFFDTDILVYSTTSDPRQATAAACLEQGGFASVQVLNEFVHVARRKLRHDWPQIEMALEQFRAALDDVRPITLGTHVA
AVALARDHLLSFYDALIVAAAQEAGCDVLYSEDLQHGRTFGSLRVENPFLEGSR

Nucleotide

• Length: 405 bp

>T167956 NZ_CP075487:3426055-3426273 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8879.15 Da
• Isoelectric Point: 5.2072

>AT167956 WP_119017290.1 NZ_CP058907:c3843303-3843073 [Rhodopseudomonas palustris]
MKVSKWGNSLAVRLPNALVDRLELKEGDELNVVDVVERTLVVEKEDRRKAAVERLSKLRWTLPPDYKFDRDESNEL

Nucleotide

• Length: 231 bp

>AT167956 NZ_CP075487:3425655-3426029 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG