Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1961456..1961727 Replicon chromosome
Accession NZ_CP058886
Organism Shigella flexneri strain STLEFF_33

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1961586..1961689 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1961456..1961727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT25_RS09500 1958011..1958673 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZT25_RS09505 1958697..1959353 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HZT25_RS09510 1959455..1959685 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT25_RS09515 1959824..1960198 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HZT25_RS09520 1960202..1961074 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HZT25_RS09525 1961087..1961428 + 342 WP_000976476.1 YebY family protein -
- 1961456..1961727 - 272 - - Antitoxin
- 1961586..1961689 + 104 - - Toxin
HZT25_RS09530 1961824..1962480 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HZT25_RS09535 1962481..1962672 - 192 WP_000457842.1 YebW family protein -
HZT25_RS09540 1962777..1963013 - 237 WP_001295499.1 YebV family protein -
HZT25_RS09545 1963131..1964570 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167931 NZ_CP058886:1961586-1961689 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167931 NZ_CP058886:c1961727-1961456 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References