Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1939576..1939721 Replicon chromosome
Accession NZ_CP058869
Organism Klebsiella pneumoniae strain STLEFF_44

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1939612..1939714 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1939576..1939721 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT31_RS09530 1934706..1936766 + 2061 WP_004151449.1 oligopeptidase B -
HZT31_RS09535 1936770..1937429 - 660 WP_002911407.1 exodeoxyribonuclease X -
HZT31_RS09540 1937508..1937738 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HZT31_RS09545 1937851..1938225 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HZT31_RS09550 1938229..1939098 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
HZT31_RS09555 1939115..1939453 + 339 WP_009307539.1 YebY family protein -
- 1939576..1939721 - 146 - - Antitoxin
- 1939612..1939714 + 103 - - Toxin
HZT31_RS09560 1940090..1940233 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HZT31_RS09565 1940338..1941306 - 969 WP_004151446.1 VirK/YbjX family protein -
HZT31_RS09570 1941463..1942116 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
HZT31_RS09575 1942113..1942304 - 192 WP_002911395.1 YebW family protein -
HZT31_RS09580 1942402..1942641 - 240 WP_002911393.1 YebV family protein -
HZT31_RS09585 1942757..1944190 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T167822 NZ_CP058869:1939612-1939714 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT167822 NZ_CP058869:c1939721-1939576 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References