Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1871676..1871821 Replicon chromosome
Accession NZ_CP058866
Organism Klebsiella pneumoniae strain STLEFF_42

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1871712..1871814 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1871676..1871821 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT30_RS09010 1866806..1868866 + 2061 WP_004151449.1 oligopeptidase B -
HZT30_RS09015 1868870..1869529 - 660 WP_020324964.1 exodeoxyribonuclease X -
HZT30_RS09020 1869608..1869838 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HZT30_RS09025 1869951..1870325 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HZT30_RS09030 1870329..1871198 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HZT30_RS09035 1871215..1871553 + 339 WP_002911404.1 YebY family protein -
- 1871676..1871821 - 146 - - Antitoxin
- 1871712..1871814 + 103 - - Toxin
HZT30_RS09040 1872190..1872333 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HZT30_RS09045 1872438..1873406 - 969 WP_004151446.1 VirK/YbjX family protein -
HZT30_RS09050 1873563..1874216 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HZT30_RS09055 1874213..1874404 - 192 WP_002911395.1 YebW family protein -
HZT30_RS09060 1874502..1874741 - 240 WP_002911393.1 YebV family protein -
HZT30_RS09065 1874857..1876290 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T167802 NZ_CP058866:1871712-1871814 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT167802 NZ_CP058866:c1871821-1871676 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References