Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2026915..2027059 | Replicon | chromosome |
| Accession | NZ_CP058857 | ||
| Organism | Klebsiella pneumoniae strain STLE2 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2026951..2027053 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2026915..2027059 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZT19_RS09845 (HZT19_09850) | 2022045..2024105 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HZT19_RS09850 (HZT19_09855) | 2024109..2024768 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HZT19_RS09855 (HZT19_09860) | 2024847..2025077 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HZT19_RS09860 (HZT19_09865) | 2025190..2025564 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| HZT19_RS09865 (HZT19_09870) | 2025568..2026437 | + | 870 | WP_020956678.1 | copper homeostasis membrane protein CopD | - |
| HZT19_RS09870 (HZT19_09875) | 2026454..2026792 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2026915..2027059 | - | 145 | - | - | Antitoxin |
| - | 2026951..2027053 | + | 103 | - | - | Toxin |
| HZT19_RS09875 (HZT19_09880) | 2027186..2027467 | - | 282 | Protein_1930 | tyrosine-type recombinase/integrase | - |
| HZT19_RS09880 (HZT19_09885) | 2027544..2028023 | + | 480 | WP_032419797.1 | lysis protein | - |
| HZT19_RS09885 | 2028478..2028673 | + | 196 | Protein_1932 | DNA polymerase V | - |
| HZT19_RS09890 (HZT19_09890) | 2028812..2030317 | + | 1506 | WP_020956680.1 | hypothetical protein | - |
| HZT19_RS09895 (HZT19_09895) | 2030567..2030995 | - | 429 | WP_032419788.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| HZT19_RS09900 (HZT19_09900) | 2031005..2031286 | - | 282 | WP_032419786.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T167764 NZ_CP058857:2026951-2027053 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 145 bp
>AT167764 NZ_CP058857:c2027059-2026915 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
