Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2448195..2448466 | Replicon | chromosome |
| Accession | NZ_CP058853 | ||
| Organism | Shigella flexneri strain STLEFF_38 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2448233..2448336 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2448195..2448466 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZT29_RS11900 | 2445352..2446791 | + | 1440 | WP_001338165.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| HZT29_RS11905 | 2446909..2447145 | + | 237 | WP_001338166.1 | YebV family protein | - |
| HZT29_RS11910 | 2447250..2447441 | + | 192 | WP_001338167.1 | YebW family protein | - |
| HZT29_RS11915 | 2447442..2448098 | - | 657 | WP_000812733.1 | protein-serine/threonine phosphatase | - |
| - | 2448195..2448466 | + | 272 | - | - | Antitoxin |
| - | 2448233..2448336 | - | 104 | - | - | Toxin |
| HZT29_RS11920 | 2448494..2448835 | - | 342 | WP_000976472.1 | YebY family protein | - |
| HZT29_RS11925 | 2448848..2449720 | - | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| HZT29_RS11930 | 2449724..2450098 | - | 375 | WP_000255065.1 | CopC domain-containing protein YobA | - |
| HZT29_RS11935 | 2450237..2450467 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HZT29_RS11940 | 2450569..2451225 | + | 657 | WP_000011660.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HZT29_RS11945 | 2451249..2451911 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T167743 NZ_CP058853:c2448336-2448233 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT167743 NZ_CP058853:2448195-2448466 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
