Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2423176..2423447 | Replicon | chromosome |
| Accession | NZ_CP058846 | ||
| Organism | Shigella flexneri strain STLEFF_35 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2423214..2423317 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2423176..2423447 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZT27_RS11775 | 2420333..2421772 | + | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| HZT27_RS11780 | 2421890..2422126 | + | 237 | WP_001295499.1 | YebV family protein | - |
| HZT27_RS11785 | 2422231..2422422 | + | 192 | WP_001296140.1 | YebW family protein | - |
| HZT27_RS11790 | 2422423..2423079 | - | 657 | WP_000812724.1 | protein-serine/threonine phosphatase | - |
| - | 2423176..2423447 | + | 272 | - | - | Antitoxin |
| - | 2423214..2423317 | - | 104 | - | - | Toxin |
| HZT27_RS11795 | 2423474..2423815 | - | 342 | WP_000976472.1 | YebY family protein | - |
| HZT27_RS11800 | 2423828..2424700 | - | 873 | WP_000879294.1 | copper homeostasis membrane protein CopD | - |
| HZT27_RS11805 | 2424704..2425078 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| HZT27_RS11810 | 2425217..2425447 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HZT27_RS11815 | 2425549..2426205 | + | 657 | WP_000011657.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HZT27_RS11820 | 2426229..2426891 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T167690 NZ_CP058846:c2423317-2423214 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT167690 NZ_CP058846:2423176-2423447 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
