Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 998078..998349 Replicon chromosome
Accession NZ_CP058839
Organism Shigella flexneri strain STLEFF_34

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 998116..998219 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 998078..998349 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT26_RS04990 995235..996674 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HZT26_RS04995 996792..997028 + 237 WP_001295499.1 YebV family protein -
HZT26_RS05000 997133..997324 + 192 WP_000457842.1 YebW family protein -
HZT26_RS05005 997325..997981 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 998078..998349 + 272 - - Antitoxin
- 998116..998219 - 104 - - Toxin
HZT26_RS05010 998377..998718 - 342 WP_000976476.1 YebY family protein -
HZT26_RS05015 998731..999603 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HZT26_RS05020 999607..999981 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HZT26_RS05025 1000120..1000350 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT26_RS05030 1000452..1001108 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HZT26_RS05035 1001132..1001794 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167653 NZ_CP058839:c998219-998116 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167653 NZ_CP058839:998078-998349 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References