Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1919703..1919974 Replicon chromosome
Accession NZ_CP058831
Organism Shigella flexneri strain STLE4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1919833..1919936 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1919703..1919974 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT21_RS09195 1916258..1916920 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZT21_RS09200 1916944..1917600 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HZT21_RS09205 1917702..1917932 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT21_RS09210 1918071..1918445 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HZT21_RS09215 1918449..1919321 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HZT21_RS09220 1919334..1919675 + 342 WP_000976476.1 YebY family protein -
- 1919703..1919974 - 272 - - Antitoxin
- 1919833..1919936 + 104 - - Toxin
HZT21_RS09225 1920071..1920727 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HZT21_RS09230 1920728..1920919 - 192 WP_000457842.1 YebW family protein -
HZT21_RS09235 1921024..1921260 - 237 WP_001295499.1 YebV family protein -
HZT21_RS09240 1921378..1922817 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167606 NZ_CP058831:1919833-1919936 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167606 NZ_CP058831:c1919974-1919703 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References