Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1997355..1997626 | Replicon | chromosome |
| Accession | NZ_CP058826 | ||
| Organism | Shigella flexneri strain STLE1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1997485..1997588 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1997355..1997626 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HZT18_RS09625 | 1993910..1994572 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| HZT18_RS09630 | 1994596..1995252 | - | 657 | WP_000011660.1 | carbon-nitrogen hydrolase family protein YobB | - |
| HZT18_RS09635 | 1995354..1995584 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| HZT18_RS09640 | 1995723..1996097 | + | 375 | WP_000255065.1 | CopC domain-containing protein YobA | - |
| HZT18_RS09645 | 1996101..1996973 | + | 873 | WP_000879298.1 | copper homeostasis membrane protein CopD | - |
| HZT18_RS09650 | 1996986..1997327 | + | 342 | WP_174784690.1 | YebY family protein | - |
| - | 1997355..1997626 | - | 272 | - | - | Antitoxin |
| - | 1997485..1997588 | + | 104 | - | - | Toxin |
| HZT18_RS09655 | 1997723..1998379 | + | 657 | WP_000812733.1 | protein-serine/threonine phosphatase | - |
| HZT18_RS09660 | 1998380..1998571 | - | 192 | WP_001338167.1 | YebW family protein | - |
| HZT18_RS09665 | 1998676..1998912 | - | 237 | WP_001338166.1 | YebV family protein | - |
| HZT18_RS09670 | 1999030..2000469 | - | 1440 | WP_001338165.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T167559 NZ_CP058826:1997485-1997588 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT167559 NZ_CP058826:c1997626-1997355 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
