Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2057144..2057415 Replicon chromosome
Accession NZ_CP058796
Organism Shigella flexneri strain STLIN_8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2057274..2057377 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2057144..2057415 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT12_RS10030 2053699..2054361 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZT12_RS10035 2054385..2055041 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
HZT12_RS10040 2055143..2055373 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT12_RS10045 2055512..2055886 + 375 WP_000168738.1 CopC domain-containing protein YobA -
HZT12_RS10050 2055890..2056762 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
HZT12_RS10055 2056775..2057116 + 342 WP_000976472.1 YebY family protein -
- 2057144..2057415 - 272 - - Antitoxin
- 2057274..2057377 + 104 - - Toxin
HZT12_RS10060 2057512..2058168 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
HZT12_RS10065 2058169..2058360 - 192 WP_001313035.1 YebW family protein -
HZT12_RS10070 2058465..2058701 - 237 WP_001295499.1 YebV family protein -
HZT12_RS10075 2058819..2060258 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167535 NZ_CP058796:2057274-2057377 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167535 NZ_CP058796:c2057415-2057144 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References