Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2040848..2041119 Replicon chromosome
Accession NZ_CP058790
Organism Shigella flexneri strain STLIN_6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2040978..2041081 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2040848..2041119 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT08_RS09890 2037403..2038065 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZT08_RS09895 2038089..2038745 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HZT08_RS09900 2038847..2039077 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT08_RS09905 2039216..2039590 + 375 WP_000204700.1 CopC domain-containing protein YobA -
HZT08_RS09910 2039594..2040466 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HZT08_RS09915 2040479..2040820 + 342 WP_000976472.1 YebY family protein -
- 2040848..2041119 - 272 - - Antitoxin
- 2040978..2041081 + 104 - - Toxin
HZT08_RS09920 2041216..2041872 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
HZT08_RS09925 2041873..2042064 - 192 WP_001296140.1 YebW family protein -
HZT08_RS09930 2042169..2042405 - 237 WP_001295499.1 YebV family protein -
HZT08_RS09935 2042523..2043962 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167500 NZ_CP058790:2040978-2041081 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167500 NZ_CP058790:c2041119-2040848 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References