Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2015675..2015946 Replicon chromosome
Accession NZ_CP058786
Organism Shigella flexneri strain STLIN_4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2015805..2015908 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2015675..2015946 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT07_RS09815 2012230..2012892 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZT07_RS09820 2012916..2013572 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HZT07_RS09825 2013674..2013904 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT07_RS09830 2014043..2014417 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HZT07_RS09835 2014421..2015293 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HZT07_RS09840 2015306..2015647 + 342 WP_000976476.1 YebY family protein -
- 2015675..2015946 - 272 - - Antitoxin
- 2015805..2015908 + 104 - - Toxin
HZT07_RS09845 2016043..2016699 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HZT07_RS09850 2016700..2016891 - 192 WP_000457842.1 YebW family protein -
HZT07_RS09855 2016996..2017232 - 237 WP_001295499.1 YebV family protein -
HZT07_RS09860 2017350..2018789 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167473 NZ_CP058786:2015805-2015908 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167473 NZ_CP058786:c2015946-2015675 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References