Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2711198..2711469 Replicon chromosome
Accession NZ_CP058771
Organism Shigella flexneri strain STLIN_11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2711236..2711339 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2711198..2711469 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZS97_RS13065 2708355..2709794 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HZS97_RS13070 2709912..2710148 + 237 WP_001295499.1 YebV family protein -
HZS97_RS13075 2710253..2710444 + 192 WP_000457842.1 YebW family protein -
HZS97_RS13080 2710445..2711101 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2711198..2711469 + 272 - - Antitoxin
- 2711236..2711339 - 104 - - Toxin
HZS97_RS13085 2711497..2711838 - 342 WP_000976476.1 YebY family protein -
HZS97_RS13090 2711851..2712723 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HZS97_RS13095 2712727..2713101 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HZS97_RS13100 2713240..2713470 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HZS97_RS13105 2713572..2714228 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
HZS97_RS13110 2714252..2714914 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167419 NZ_CP058771:c2711339-2711236 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167419 NZ_CP058771:2711198-2711469 [Shigella flexneri]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References