Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 552791..552936 Replicon chromosome
Accession NZ_CP058752
Organism Klebsiella pneumoniae strain STLIN_19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 552827..552929 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 552791..552936 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT05_RS02730 547921..549981 + 2061 WP_004151449.1 oligopeptidase B -
HZT05_RS02735 549985..550644 - 660 WP_002911407.1 exodeoxyribonuclease X -
HZT05_RS02740 550723..550953 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HZT05_RS02745 551066..551440 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HZT05_RS02750 551444..552313 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
HZT05_RS02755 552330..552668 + 339 WP_240726274.1 YebY family protein -
- 552791..552936 - 146 - - Antitoxin
- 552827..552929 + 103 - - Toxin
HZT05_RS02760 553305..553448 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HZT05_RS02765 553553..554521 - 969 WP_004151446.1 VirK/YbjX family protein -
HZT05_RS02770 554678..555331 + 654 WP_038807473.1 protein-serine/threonine phosphatase -
HZT05_RS02775 555328..555519 - 192 WP_002911395.1 YebW family protein -
HZT05_RS02780 555617..555856 - 240 WP_002911393.1 YebV family protein -
HZT05_RS02785 555972..557405 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 482067..570334 88267


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T167364 NZ_CP058752:552827-552929 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT167364 NZ_CP058752:c552936-552791 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References