Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1945460..1945605 Replicon chromosome
Accession NZ_CP058743
Organism Klebsiella pneumoniae strain STLIN_10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1945496..1945598 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1945460..1945605 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZS96_RS09580 1940590..1942650 + 2061 WP_004151449.1 oligopeptidase B -
HZS96_RS09585 1942654..1943313 - 660 WP_002911407.1 exodeoxyribonuclease X -
HZS96_RS09590 1943392..1943622 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HZS96_RS09595 1943735..1944109 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HZS96_RS09600 1944113..1944982 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
HZS96_RS09605 1944999..1945337 + 339 WP_240726274.1 YebY family protein -
- 1945460..1945605 - 146 - - Antitoxin
- 1945496..1945598 + 103 - - Toxin
HZS96_RS09610 1945974..1946117 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HZS96_RS09615 1946222..1947190 - 969 WP_004151446.1 VirK/YbjX family protein -
HZS96_RS09620 1947347..1948000 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
HZS96_RS09625 1947997..1948188 - 192 WP_002911395.1 YebW family protein -
HZS96_RS09630 1948286..1948525 - 240 WP_002911393.1 YebV family protein -
HZS96_RS09635 1948641..1950074 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1874734..1963002 88268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T167315 NZ_CP058743:1945496-1945598 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT167315 NZ_CP058743:c1945605-1945460 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References