Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | omega-epsilon-zeta/zeta-epsilon |
Location | 1245299..1245842 | Replicon | chromosome |
Accession | NZ_CP058740 | ||
Organism | Streptococcus suis strain 16085/3b |
Toxin (Protein)
Gene name | zeta | Uniprot ID | A0A1X9I2P4 |
Locus tag | SSU16085_RS05955 | Protein ID | WP_002943355.1 |
Coordinates | 1245573..1245842 (+) | Length | 90 a.a. |
Antitoxin (Protein)
Gene name | epsilon | Uniprot ID | Q9AL19 |
Locus tag | SSU16085_RS05950 | Protein ID | WP_002326825.1 |
Coordinates | 1245299..1245571 (+) | Length | 91 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SSU16085_RS05905 | 1240553..1240783 | + | 231 | WP_000659121.1 | hypothetical protein | - |
SSU16085_RS05910 | 1240854..1241045 | + | 192 | WP_000503424.1 | hypothetical protein | - |
SSU16085_RS05915 | 1241099..1242202 | + | 1104 | Protein_1135 | recombinase family protein | - |
SSU16085_RS05920 | 1242291..1242530 | + | 240 | WP_000635249.1 | peptide-binding protein | - |
SSU16085_RS05925 | 1242579..1242662 | + | 84 | WP_001814874.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
SSU16085_RS05930 | 1242787..1243524 | + | 738 | WP_001038795.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) | - |
SSU16085_RS05935 | 1243694..1243954 | + | 261 | Protein_1139 | topoisomerase DNA-binding C4 zinc finger domain-containing protein | - |
SSU16085_RS05940 | 1244057..1244953 | + | 897 | WP_002326827.1 | ParA family protein | - |
SSU16085_RS05945 | 1245072..1245281 | + | 210 | WP_000527318.1 | peptide-binding protein | - |
SSU16085_RS05950 | 1245299..1245571 | + | 273 | WP_002326825.1 | antitoxin | Antitoxin |
SSU16085_RS05955 | 1245573..1245842 | + | 270 | WP_002943355.1 | zeta toxin family protein | Toxin |
SSU16085_RS05960 | 1245940..1246287 | + | 348 | Protein_1144 | DUF4368 domain-containing protein | - |
SSU16085_RS05965 | 1246254..1247213 | + | 960 | Protein_1145 | hypothetical protein | - |
SSU16085_RS05970 | 1247284..1247583 | + | 300 | WP_024408864.1 | hypothetical protein | - |
SSU16085_RS05975 | 1247597..1247887 | + | 291 | WP_024408865.1 | membrane protein | - |
SSU16085_RS05980 | 1247983..1248621 | + | 639 | WP_192062955.1 | peptidylprolyl isomerase | - |
SSU16085_RS05985 | 1248660..1249736 | + | 1077 | WP_044763948.1 | toprim domain-containing protein | - |
SSU16085_RS05990 | 1249790..1250017 | + | 228 | WP_000110922.1 | hypothetical protein | - |
SSU16085_RS05995 | 1250014..1250403 | + | 390 | WP_000048066.1 | hypothetical protein | - |
SSU16085_RS06000 | 1250453..1250749 | + | 297 | WP_002936411.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | tet(O) / erm(B) | - | 1103839..1298421 | 194582 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 9999.08 Da Isoelectric Point: 8.7696
>T167299 WP_002943355.1 NZ_CP058740:1245573-1245842 [Streptococcus suis]
MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSGKTSLRSAISEETQGNVVIIDNDTFKQQHPRSTFAN
VNKRNNFNS
MANITDFTEKQFEDRLEKNVERLTKNRLAVESPTAFLLGGQPGSGKTSLRSAISEETQGNVVIIDNDTFKQQHPRSTFAN
VNKRNNFNS
Download Length: 270 bp
>T167299 NZ_CP075111:76040-76615 [Salmonella enterica]
ATGAACCACACACCTTATCCCGTAGTTTTAGATGCTTGCGTACTGTATCCGTCATTTCTACGGGATTTACTGATTCGATT
GGGGCTGACCGGGTTGTACCAACCAAAATGGTCAGCCAGCATCGAAAATGAGTGGCAACGTAACCTGTTAGCAAACAGAA
CGGATCTAACTGAAGAGCAAATTAAACGCACTGCCACGCTAATGAATAAAGCCGTTCCTGATGCGTTGGTTACCGGCTTT
GAGCCTCTGATTGATAGCATTGATTTACCTGATGTAGATGATCGGCATGTTGCCGCAGCTGCTGTCCGTAGCAATGCTGA
AATCATTGTGACGTTGAATCTTAAAGATTTTCCGGCACCTGCTCTTGATGCCTTTGGTATCGAAGCGTTACATCCTGACG
ATTTTGTTATGGATTTATTCGATTTAAATAGAGCACTTGTGCTTTCGGCCGTAACTACGCAGCGCAGTAGTTTACGGAAA
CCGCCCGTGTCGGTTGATGAATATTTAGAAGCGCTGCTAAGGCAAGGTATGGCGCAAACCGTAAAAGAATTAAGCAAATA
CCGCATGCTGATTTAG
ATGAACCACACACCTTATCCCGTAGTTTTAGATGCTTGCGTACTGTATCCGTCATTTCTACGGGATTTACTGATTCGATT
GGGGCTGACCGGGTTGTACCAACCAAAATGGTCAGCCAGCATCGAAAATGAGTGGCAACGTAACCTGTTAGCAAACAGAA
CGGATCTAACTGAAGAGCAAATTAAACGCACTGCCACGCTAATGAATAAAGCCGTTCCTGATGCGTTGGTTACCGGCTTT
GAGCCTCTGATTGATAGCATTGATTTACCTGATGTAGATGATCGGCATGTTGCCGCAGCTGCTGTCCGTAGCAATGCTGA
AATCATTGTGACGTTGAATCTTAAAGATTTTCCGGCACCTGCTCTTGATGCCTTTGGTATCGAAGCGTTACATCCTGACG
ATTTTGTTATGGATTTATTCGATTTAAATAGAGCACTTGTGCTTTCGGCCGTAACTACGCAGCGCAGTAGTTTACGGAAA
CCGCCCGTGTCGGTTGATGAATATTTAGAAGCGCTGCTAAGGCAAGGTATGGCGCAAACCGTAAAAGAATTAAGCAAATA
CCGCATGCTGATTTAG
Antitoxin
Download Length: 91 a.a. Molecular weight: 10720.17 Da Isoelectric Point: 4.4865
>AT167299 WP_002326825.1 NZ_CP058740:1245299-1245571 [Streptococcus suis]
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVNLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYS
KQILTKEKVA
MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELDTKNTRLLEVNLLNQLEVAQEVDLFQQPFEELQAIHEYWRSMNQYS
KQILTKEKVA
Download Length: 273 bp
>AT167299 NZ_CP075111:75579-76040 [Salmonella enterica]
ATGACAAACTCAATTCTTGATAGCCTTAGCCTTCCGGCTAAAGGGGAGATTGAGGCAGCTGTACGTGGACAAAGGGAGCT
TGCCGCCTACCTCTCCACAAAAATGGAAACACAGAAAATTTCGATTCAGGATGCAGATAACGTAACTCATCAAATCGAAC
TACCGACGTCTTCACTGACGTTGCTTATGTCGATTTTGGGTGAACTAGCACTTGGTAACGCGGTGCAAGTCGTTCCTGTG
CATGCTGAATTGACCACGCAGGAAGCCGCCAATATTCTTAATGTTTCACGCCCTCATATGGTGAAACTGCTGGAAGAGGG
GAAGCTGCCTTTTCATAAAACAGGTCGCCATCGCCGCGTGCTTTTCGCCGATTTGATGAAGTACAAGGATCAGCGAGATA
GCGATAGCAATATAGCTATGCAGGAGTTGGCAGATCTAAGCCAAGAGCTTGGACTTTACTAA
ATGACAAACTCAATTCTTGATAGCCTTAGCCTTCCGGCTAAAGGGGAGATTGAGGCAGCTGTACGTGGACAAAGGGAGCT
TGCCGCCTACCTCTCCACAAAAATGGAAACACAGAAAATTTCGATTCAGGATGCAGATAACGTAACTCATCAAATCGAAC
TACCGACGTCTTCACTGACGTTGCTTATGTCGATTTTGGGTGAACTAGCACTTGGTAACGCGGTGCAAGTCGTTCCTGTG
CATGCTGAATTGACCACGCAGGAAGCCGCCAATATTCTTAATGTTTCACGCCCTCATATGGTGAAACTGCTGGAAGAGGG
GAAGCTGCCTTTTCATAAAACAGGTCGCCATCGCCGCGTGCTTTTCGCCGATTTGATGAAGTACAAGGATCAGCGAGATA
GCGATAGCAATATAGCTATGCAGGAGTTGGCAGATCTAAGCCAAGAGCTTGGACTTTACTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X9I2P4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0M2AF93 |