Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4732067..4732338 Replicon chromosome
Accession NZ_CP058714
Organism Escherichia coli strain M172-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4732105..4732207 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4732067..4732338 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYI45_RS22645 4729224..4730663 + 1440 WP_024175799.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HYI45_RS22650 4730781..4731017 + 237 WP_001295499.1 YebV family protein -
HYI45_RS22655 4731122..4731313 + 192 WP_001296140.1 YebW family protein -
HYI45_RS22660 4731314..4731970 - 657 WP_000812749.1 protein-serine/threonine phosphatase -
- 4732067..4732338 + 272 - - Antitoxin
- 4732105..4732207 - 103 - - Toxin
HYI45_RS22665 4732366..4732707 - 342 WP_072775549.1 YebY family protein -
HYI45_RS22670 4732720..4733592 - 873 WP_000879322.1 copper homeostasis membrane protein CopD -
HYI45_RS22675 4733596..4733970 - 375 WP_000168737.1 CopC domain-containing protein YobA -
HYI45_RS22680 4734109..4734339 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HYI45_RS22685 4734441..4735097 + 657 WP_000011663.1 carbon-nitrogen hydrolase family protein YobB -
HYI45_RS22690 4735121..4735783 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T167224 NZ_CP058714:c4732207-4732105 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167224 NZ_CP058714:4732067-4732338 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGATTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References