Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | yfjZ-ypjF/CbtA-CbeA |
Location | 784011..784717 | Replicon | chromosome |
Accession | NZ_CP058714 | ||
Organism | Escherichia coli strain M172-1 |
Toxin (Protein)
Gene name | ypjF | Uniprot ID | V0SXW1 |
Locus tag | HYI45_RS03910 | Protein ID | WP_000854677.1 |
Coordinates | 784011..784379 (-) | Length | 123 a.a. |
Antitoxin (Protein)
Gene name | yfjZ | Uniprot ID | V0SU84 |
Locus tag | HYI45_RS03915 | Protein ID | WP_000065824.1 |
Coordinates | 784400..784717 (-) | Length | 106 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HYI45_RS03890 (779391) | 779391..781034 | + | 1644 | WP_001265639.1 | fimbrial adhesin EcpD | - |
HYI45_RS03895 (781003) | 781003..781713 | + | 711 | WP_001361803.1 | fimbrial chaperone EcpE | - |
HYI45_RS03900 (782026) | 782026..782355 | + | 330 | WP_001303809.1 | YkgJ family cysteine cluster protein | - |
HYI45_RS03905 (782604) | 782604..783218 | - | 615 | WP_001019920.1 | YagU family protein | - |
HYI45_RS03910 (784011) | 784011..784379 | - | 369 | WP_000854677.1 | TA system toxin CbtA family protein | Toxin |
HYI45_RS03915 (784400) | 784400..784717 | - | 318 | WP_000065824.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
HYI45_RS03920 (784737) | 784737..784958 | - | 222 | WP_001220307.1 | DUF987 domain-containing protein | - |
HYI45_RS03925 (784967) | 784967..785446 | - | 480 | WP_000438147.1 | RadC family protein | - |
HYI45_RS03930 (785458) | 785458..785916 | - | 459 | WP_000211834.1 | antirestriction protein | - |
HYI45_RS03935 (786002) | 786002..786238 | - | 237 | Protein_772 | DUF905 domain-containing protein | - |
HYI45_RS03945 (787722) | 787722..787873 | - | 152 | Protein_774 | IS3 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fdeC / ykgK/ecpR / yagZ/ecpA / yagY/ecpB / yagX/ecpC / yagW/ecpD / yagV/ecpE | 756761..795703 | 38942 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13687.89 Da Isoelectric Point: 8.2671
>T167210 WP_000854677.1 NZ_CP058714:c784379-784011 [Escherichia coli]
MKTLPATTPQAAKPCLSPVSVWQMLLTRLLEQHYGLMLSDTPFSDETVIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTTTDILQARKACGLMSRCSYREVSNIVLSRSRL
MKTLPATTPQAAKPCLSPVSVWQMLLTRLLEQHYGLMLSDTPFSDETVIKEHIDAGITLANAVNFLVEKYELVRIDRNGF
TSQVQAPYLTTTDILQARKACGLMSRCSYREVSNIVLSRSRL
Download Length: 369 bp
>T167210 NZ_CP075061:4689232-4689552 [Escherichia coli]
ATGAAAACTCAACCTGCAACAACTCCGCAGGCGGCGAAGCCATGTCTGTCGCCCCTGGCTGTCTGGCAAATGTTACTGAC
AAGCCTGCTAGACCAGCACTATGGTCTCACGCTAAACGACACGCCGTTCAGTGATGAAACTGTTATTCAGAAACACATTG
AGGCAGGTATTACCTTGGCCGATGCCGTAAACTTTCTGGTTGAACGCTATGAACTAGTTCGTATTGACCAAAAAGGCTTC
TCTGTGCAAGATCAAGAACCTTGGTTAACCTCTATGGATGTTCACCGAGCACGATTTAAACTCAACGTGGAACGTTTATA
A
ATGAAAACTCAACCTGCAACAACTCCGCAGGCGGCGAAGCCATGTCTGTCGCCCCTGGCTGTCTGGCAAATGTTACTGAC
AAGCCTGCTAGACCAGCACTATGGTCTCACGCTAAACGACACGCCGTTCAGTGATGAAACTGTTATTCAGAAACACATTG
AGGCAGGTATTACCTTGGCCGATGCCGTAAACTTTCTGGTTGAACGCTATGAACTAGTTCGTATTGACCAAAAAGGCTTC
TCTGTGCAAGATCAAGAACCTTGGTTAACCTCTATGGATGTTCACCGAGCACGATTTAAACTCAACGTGGAACGTTTATA
A
Antitoxin
Download Length: 106 a.a. Molecular weight: 11964.46 Da Isoelectric Point: 6.3163
>AT167210 WP_000065824.1 NZ_CP058714:c784717-784400 [Escherichia coli]
MSNITWGLQRDITPRLGARLVQEGNQLHYLADRASITGKFSDAEYRKLDETFPHFISQMESMLTTGEMNPRHAHCVTLYH
DGFTCEADTLGSCGYVYIVVYSTQR
MSNITWGLQRDITPRLGARLVQEGNQLHYLADRASITGKFSDAEYRKLDETFPHFISQMESMLTTGEMNPRHAHCVTLYH
DGFTCEADTLGSCGYVYIVVYSTQR
Download Length: 318 bp
>AT167210 NZ_CP075061:4688885-4689211 [Escherichia coli]
ATGTCATTAATACCAGCCCATGAATGGGGACTACAAAGAGAAATTGTTCCACGGTTTGGAGCCAGATTAGTTCAGGAGGG
CAACCGGCTGCATTATCTGGCTGACAGGGCTAATTTGATGGGCAATTTCAGCGATACGGAATGCTTCAAATTGAATGACG
CATTTCCACACTTTATCAGTCAGATGGAATCGATGCTGACCACTGGTGAACTAATCCCCTGTCACCATCACTGTGTCACT
CTCTACCACAACGGTTTTACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTGTACATCGCGGTTTATCCCACTCA
ACGCTAA
ATGTCATTAATACCAGCCCATGAATGGGGACTACAAAGAGAAATTGTTCCACGGTTTGGAGCCAGATTAGTTCAGGAGGG
CAACCGGCTGCATTATCTGGCTGACAGGGCTAATTTGATGGGCAATTTCAGCGATACGGAATGCTTCAAATTGAATGACG
CATTTCCACACTTTATCAGTCAGATGGAATCGATGCTGACCACTGGTGAACTAATCCCCTGTCACCATCACTGTGTCACT
CTCTACCACAACGGTTTTACCTGCGAAGCCGACACCCTTGGCAGTTGCGGCTACGTGTACATCGCGGTTTATCCCACTCA
ACGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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