Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 191581..191815 Replicon chromosome
Accession NZ_CP058709
Organism Escherichia coli strain S163-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 191711..191814 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 191581..191815 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZS88_RS00980 188136..188798 - 663 WP_000944258.1 exodeoxyribonuclease X -
HZS88_RS00985 188822..189478 - 657 WP_063121046.1 carbon-nitrogen hydrolase family protein YobB -
HZS88_RS00990 189580..189810 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZS88_RS00995 189949..190323 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HZS88_RS01000 190327..191199 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
HZS88_RS01005 191212..191553 + 342 WP_000976472.1 YebY family protein -
- 191581..191815 - 235 - - Antitoxin
- 191711..191814 + 104 - - Toxin
HZS88_RS01010 191946..193022 - 1077 WP_087891211.1 phage integrase Arm DNA-binding domain-containing protein -
HZS88_RS01015 192988..193269 - 282 WP_001311878.1 excisionase -
HZS88_RS01020 193376..193564 - 189 WP_001356607.1 DUF1187 family protein -
- 193380..193558 + 179 NuclAT_0 - -
- 193380..193558 + 179 NuclAT_0 - -
- 193380..193558 + 179 NuclAT_0 - -
- 193380..193558 + 179 NuclAT_0 - -
HZS88_RS01025 193557..193751 - 195 WP_071780718.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
HZS88_RS01030 193815..194867 - 1053 WP_001004419.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 186079..249904 63825


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167179 NZ_CP058709:191711-191814 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT167179 NZ_CP058709:c191815-191581 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References