Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
Location | 191581..191815 | Replicon | chromosome |
Accession | NZ_CP058709 | ||
Organism | Escherichia coli strain S163-2 |
Toxin (RNA)
Gene name | SdsR | ||
Locus tag | - | ||
Coordinates | 191711..191814 (+) |
Antitoxin (RNA)
Gene name | RyeA | ||
Locus tag | - | ||
Coordinates | 191581..191815 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HZS88_RS00980 | 188136..188798 | - | 663 | WP_000944258.1 | exodeoxyribonuclease X | - |
HZS88_RS00985 | 188822..189478 | - | 657 | WP_063121046.1 | carbon-nitrogen hydrolase family protein YobB | - |
HZS88_RS00990 | 189580..189810 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
HZS88_RS00995 | 189949..190323 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
HZS88_RS01000 | 190327..191199 | + | 873 | WP_000879295.1 | copper homeostasis membrane protein CopD | - |
HZS88_RS01005 | 191212..191553 | + | 342 | WP_000976472.1 | YebY family protein | - |
- | 191581..191815 | - | 235 | - | - | Antitoxin |
- | 191711..191814 | + | 104 | - | - | Toxin |
HZS88_RS01010 | 191946..193022 | - | 1077 | WP_087891211.1 | phage integrase Arm DNA-binding domain-containing protein | - |
HZS88_RS01015 | 192988..193269 | - | 282 | WP_001311878.1 | excisionase | - |
HZS88_RS01020 | 193376..193564 | - | 189 | WP_001356607.1 | DUF1187 family protein | - |
- | 193380..193558 | + | 179 | NuclAT_0 | - | - |
- | 193380..193558 | + | 179 | NuclAT_0 | - | - |
- | 193380..193558 | + | 179 | NuclAT_0 | - | - |
- | 193380..193558 | + | 179 | NuclAT_0 | - | - |
HZS88_RS01025 | 193557..193751 | - | 195 | WP_071780718.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
HZS88_RS01030 | 193815..194867 | - | 1053 | WP_001004419.1 | RecT family recombinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 186079..249904 | 63825 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T167179 NZ_CP058709:191711-191814 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT167179 NZ_CP058709:c191815-191581 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT