Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2476695..2476929 Replicon chromosome
Accession NZ_CP058682
Organism Escherichia coli strain MBT-5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2476825..2476928 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2476695..2476929 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZT35_RS12465 2473250..2473912 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZT35_RS12470 2473936..2474592 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HZT35_RS12475 2474694..2474924 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZT35_RS12480 2475063..2475437 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HZT35_RS12485 2475441..2476313 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HZT35_RS12490 2476326..2476667 + 342 WP_000976492.1 YebY family protein -
- 2476695..2476929 - 235 - - Antitoxin
- 2476825..2476928 + 104 - - Toxin
HZT35_RS12495 2477060..2478136 - 1077 WP_001189091.1 phage integrase Arm DNA-binding domain-containing protein -
HZT35_RS12500 2478102..2478383 - 282 WP_001443927.1 excisionase -
HZT35_RS12505 2478490..2478678 - 189 WP_001356607.1 DUF1187 family protein -
- 2478494..2478672 + 179 NuclAT_1 - -
- 2478494..2478672 + 179 NuclAT_1 - -
- 2478494..2478672 + 179 NuclAT_1 - -
- 2478494..2478672 + 179 NuclAT_1 - -
HZT35_RS12510 2478671..2478865 - 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
HZT35_RS12515 2478922..2479731 - 810 WP_000166317.1 recombination protein RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2476326..2544736 68410


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167144 NZ_CP058682:2476825-2476928 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT167144 NZ_CP058682:c2476929-2476695 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References