Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1029471..1030068 Replicon chromosome
Accession NZ_CP058670
Organism Chryseoglobus indicus strain CTD02-10-2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HUJ41_RS05020 Protein ID WP_152583138.1
Coordinates 1029471..1029779 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HUJ41_RS05025 Protein ID WP_152583106.1
Coordinates 1029769..1030068 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUJ41_RS05010 1024748..1025527 - 780 WP_179873608.1 M48 family metalloprotease -
HUJ41_RS05015 1025681..1029292 + 3612 WP_179873879.1 bifunctional RecB family nuclease/DEAD/DEAH box helicase -
HUJ41_RS05020 1029471..1029779 + 309 WP_152583138.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HUJ41_RS05025 1029769..1030068 + 300 WP_152583106.1 putative addiction module antidote protein Antitoxin
HUJ41_RS05030 1030155..1030418 + 264 WP_152583105.1 ribbon-helix-helix protein, CopG family -
HUJ41_RS05035 1030456..1031769 + 1314 WP_179873609.1 plasmid pRiA4b ORF-3 family protein -
HUJ41_RS05040 1031877..1032305 + 429 WP_179873610.1 hypothetical protein -
HUJ41_RS05045 1032339..1032614 + 276 WP_179873611.1 hypothetical protein -
HUJ41_RS05050 1032608..1032952 + 345 WP_179873880.1 type II toxin-antitoxin system PemK/MazF family toxin -
HUJ41_RS05055 1032942..1033343 - 402 WP_152583100.1 DUF1622 domain-containing protein -
HUJ41_RS05060 1033367..1034317 - 951 WP_179873881.1 IS481 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11659.35 Da        Isoelectric Point: 10.1836

>T167106 WP_152583138.1 NZ_CP058670:1029471-1029779 [Chryseoglobus indicus]
IEVRKTAIFDRWLSNVKDMRAVARILVRIDRLAQGNAGDARSIGSGLWELRIDCGPGYRVYYLRRGKALVLLLCGGDKST
QSRDIERAYELASEWRGRHHES

Download         Length: 309 bp

>T167106 NZ_CP074680:2673362-2673469 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10267.51 Da        Isoelectric Point: 4.4488

>AT167106 WP_152583106.1 NZ_CP058670:1029769-1030068 [Chryseoglobus indicus]
MKAETVSRFDAADYLPDVETAAAYLEAAIEEAGDDPAVIATALGAIARSGNLSELSRRTGISREGLYKALSAEGNPSFAT
IVKVARALGLSIEFHASAP

Download         Length: 300 bp

>AT167106 NZ_CP074680:c2673309-2673248 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References