Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_31(antitoxin)
Location 521753..522370 Replicon chromosome
Accession NZ_CP058669
Organism Hyphobacterium sp. CCMP332

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HXX25_RS02665 Protein ID WP_187167731.1
Coordinates 521753..522004 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HXX25_RS02670 Protein ID WP_187166983.1
Coordinates 522014..522370 (+) Length 119 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HXX25_RS02640 516796..517971 - 1176 WP_187166978.1 VWA domain-containing protein -
HXX25_RS02645 518011..519405 - 1395 WP_187166979.1 hypothetical protein -
HXX25_RS02650 519517..520146 - 630 WP_187166980.1 CatB-related O-acetyltransferase -
HXX25_RS02655 520391..520621 - 231 WP_187166981.1 YdcH family protein -
HXX25_RS02660 520745..521659 + 915 WP_187166982.1 hydrogen peroxide-inducible genes activator -
HXX25_RS02665 521753..522004 + 252 WP_187167731.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HXX25_RS02670 522014..522370 + 357 WP_187166983.1 helix-turn-helix transcriptional regulator Antitoxin
HXX25_RS02675 522367..523260 - 894 WP_187166984.1 MoxR family ATPase -
HXX25_RS02680 523461..523721 + 261 WP_187166985.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
HXX25_RS02685 523861..524217 - 357 WP_187166986.1 hypothetical protein -
HXX25_RS02690 524369..526168 - 1800 WP_187166987.1 tetratricopeptide repeat protein -
HXX25_RS02695 526274..527008 + 735 WP_187166988.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(62-116)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9377.92 Da        Isoelectric Point: 10.5420

>T167105 WP_187167731.1 NZ_CP058669:521753-522004 [Hyphobacterium sp. CCMP332]
MRSVSYTKSALKVLRKMSRPDALRIMAEVDQFAIDPESLANNVKRLQGSDFIRLRVGDWRVIMDDQGAVLAVIRIGPRGS
VYE

Download         Length: 252 bp

>T167105 NZ_CP074680:2672826-2672933 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13006.93 Da        Isoelectric Point: 6.4735

>AT167105 WP_187166983.1 NZ_CP058669:522014-522370 [Hyphobacterium sp. CCMP332]
MQTINTPDGGIMVMLALEEYQALVDAADIAEGHRIRQRLASGEEELLPSDMVRRLVAGETPLRVWRKYRGISAADLARQA
HLSRAYISQIETGKRQPGVAALRRIATVLNADLDDLVA

Download         Length: 357 bp

>AT167105 NZ_CP074680:c2672779-2672713 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References