Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/HTH_31(antitoxin)
Location 521753..522370 Replicon chromosome
Accession NZ_CP058669
Organism Hyphobacterium sp. CCMP332

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HXX25_RS02665 Protein ID WP_187167731.1
Coordinates 521753..522004 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HXX25_RS02670 Protein ID WP_187166983.1
Coordinates 522014..522370 (+) Length 119 a.a.

Genomic Context

HXX25_RS02660HXX25_RS02665HXX25_RS02670HXX25_RS02680HXX25_RS02695HXX25_RS02640HXX25_RS02645HXX25_RS02650HXX25_RS02655HXX25_RS02675HXX25_RS02685HXX25_RS02690
Location: 520745..521659 (915 bp)
Type: Others
Protein ID: WP_187166982.1
Location: 521753..522004 (252 bp)
Type: Toxin
Protein ID: WP_187167731.1
Location: 522014..522370 (357 bp)
Type: Antitoxin
Protein ID: WP_187166983.1
Location: 523461..523721 (261 bp)
Type: Others
Protein ID: WP_187166985.1
Location: 526274..527008 (735 bp)
Type: Others
Protein ID: WP_187166988.1
Location: 516796..517971 (1176 bp)
Type: Others
Protein ID: WP_187166978.1
Location: 518011..519405 (1395 bp)
Type: Others
Protein ID: WP_187166979.1
Location: 519517..520146 (630 bp)
Type: Others
Protein ID: WP_187166980.1
Location: 520391..520621 (231 bp)
Type: Others
Protein ID: WP_187166981.1
Location: 522367..523260 (894 bp)
Type: Others
Protein ID: WP_187166984.1
Location: 523861..524217 (357 bp)
Type: Others
Protein ID: WP_187166986.1
Location: 524369..526168 (1800 bp)
Type: Others
Protein ID: WP_187166987.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HXX25_RS02640516796..517971-1176WP_187166978.1VWA domain-containing protein-
HXX25_RS02645518011..519405-1395WP_187166979.1hypothetical protein-
HXX25_RS02650519517..520146-630WP_187166980.1CatB-related O-acetyltransferase-
HXX25_RS02655520391..520621-231WP_187166981.1YdcH family protein-
HXX25_RS02660520745..521659+915WP_187166982.1hydrogen peroxide-inducible genes activator-
HXX25_RS02665521753..522004+252WP_187167731.1type II toxin-antitoxin system RelE/ParE family toxinToxin
HXX25_RS02670522014..522370+357WP_187166983.1helix-turn-helix transcriptional regulatorAntitoxin
HXX25_RS02675522367..523260-894WP_187166984.1MoxR family ATPase-
HXX25_RS02680523461..523721+261WP_187166985.1type II toxin-antitoxin system prevent-host-death family antitoxin-
HXX25_RS02685523861..524217-357WP_187166986.1hypothetical protein-
HXX25_RS02690524369..526168-1800WP_187166987.1tetratricopeptide repeat protein-
HXX25_RS02695526274..527008+735WP_187166988.1SDR family NAD(P)-dependent oxidoreductase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(62-116)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9377.92 Da        Isoelectric Point: 10.5420

>T167105 WP_187167731.1 NZ_CP058669:521753-522004 [Hyphobacterium sp. CCMP332]
MRSVSYTKSALKVLRKMSRPDALRIMAEVDQFAIDPESLANNVKRLQGSDFIRLRVGDWRVIMDDQGAVLAVIRIGPRGS
VYE

Download         Length: 252 bp

>T167105 NZ_CP074680:2672826-2672933 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 119 a.a.        Molecular weight: 13006.93 Da        Isoelectric Point: 6.4735

>AT167105 WP_187166983.1 NZ_CP058669:522014-522370 [Hyphobacterium sp. CCMP332]
MQTINTPDGGIMVMLALEEYQALVDAADIAEGHRIRQRLASGEEELLPSDMVRRLVAGETPLRVWRKYRGISAADLARQA
HLSRAYISQIETGKRQPGVAALRRIATVLNADLDDLVA

Download         Length: 357 bp

>AT167105 NZ_CP074680:c2672779-2672713 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References