Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YoeB-DinJ |
| Location | 2047408..2047933 | Replicon | chromosome |
| Accession | NZ_CP058668 | ||
| Organism | Treponema sp. B152 | ||
Toxin (Protein)
| Gene name | relB | Uniprot ID | M2SKE4 |
| Locus tag | HYB91_RS09560 | Protein ID | WP_002677039.1 |
| Coordinates | 2047670..2047933 (+) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | Q73PY2 |
| Locus tag | HYB91_RS09555 | Protein ID | WP_002677040.1 |
| Coordinates | 2047408..2047665 (+) | Length | 86 a.a. |
Genomic Context
Location: 2047408..2047665 (258 bp)
Type: Antitoxin
Protein ID: WP_002677040.1
Type: Antitoxin
Protein ID: WP_002677040.1
Location: 2047670..2047933 (264 bp)
Type: Toxin
Protein ID: WP_002677039.1
Type: Toxin
Protein ID: WP_002677039.1
Location: 2048048..2048326 (279 bp)
Type: Others
Protein ID: WP_002677038.1
Type: Others
Protein ID: WP_002677038.1
Location: 2048310..2048717 (408 bp)
Type: Others
Protein ID: WP_002677037.1
Type: Others
Protein ID: WP_002677037.1
Location: 2049099..2049314 (216 bp)
Type: Others
Protein ID: WP_002672335.1
Type: Others
Protein ID: WP_002672335.1
Location: 2049311..2049706 (396 bp)
Type: Others
Protein ID: WP_002672336.1
Type: Others
Protein ID: WP_002672336.1
Location: 2049760..2050665 (906 bp)
Type: Others
Protein ID: WP_002677034.1
Type: Others
Protein ID: WP_002677034.1
Location: 2050742..2051254 (513 bp)
Type: Others
Protein ID: WP_002677032.1
Type: Others
Protein ID: WP_002677032.1
Location: 2045807..2047075 (1269 bp)
Type: Others
Protein ID: WP_002677041.1
Type: Others
Protein ID: WP_002677041.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HYB91_RS09550 (HYB91_09515) | 2045807..2047075 | - | 1269 | WP_002677041.1 | OmpA family protein | - |
| HYB91_RS09555 (HYB91_09520) | 2047408..2047665 | + | 258 | WP_002677040.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| HYB91_RS09560 (HYB91_09525) | 2047670..2047933 | + | 264 | WP_002677039.1 | Txe/YoeB family addiction module toxin | Toxin |
| HYB91_RS09565 (HYB91_09530) | 2048048..2048326 | + | 279 | WP_002677038.1 | hypothetical protein | - |
| HYB91_RS09570 (HYB91_09535) | 2048310..2048717 | + | 408 | WP_002677037.1 | type II toxin-antitoxin system VapC family toxin | - |
| HYB91_RS09575 (HYB91_09540) | 2049099..2049314 | + | 216 | WP_002672335.1 | hypothetical protein | - |
| HYB91_RS09580 (HYB91_09545) | 2049311..2049706 | + | 396 | WP_002672336.1 | PIN domain-containing protein | - |
| HYB91_RS09585 (HYB91_09550) | 2049760..2050665 | + | 906 | WP_002677034.1 | YafY family protein | - |
| HYB91_RS09590 (HYB91_09555) | 2050742..2051254 | + | 513 | WP_002677032.1 | ClbS/DfsB family four-helix bundle protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10419.98 Da Isoelectric Point: 9.7704
>T167101 WP_002677039.1 NZ_CP058668:2047670-2047933 [Treponema sp. B152]
MIKAWDEDAWIDYVYWQTEDKKTLKRINMLIKDIERNGHNGLGSPEPLKGNLSGFWSRRIDKKNRLVYRIVDNVIQIIQC
RTHYGEK
MIKAWDEDAWIDYVYWQTEDKKTLKRINMLIKDIERNGHNGLGSPEPLKGNLSGFWSRRIDKKNRLVYRIVDNVIQIIQC
RTHYGEK
Download Length: 264 bp
>T167101 NZ_CP074680:1856665-1856919 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 9866.39 Da Isoelectric Point: 9.5364
>AT167101 WP_002677040.1 NZ_CP058668:2047408-2047665 [Treponema sp. B152]
MAQINVNIRMDSEVKQEAEQLFDSLGMNMTTAFNIFIRQSLRIGGIPFKIISDERGFYNKYNQKKLHAAAKRMNEGKYIV
HDIVE
MAQINVNIRMDSEVKQEAEQLFDSLGMNMTTAFNIFIRQSLRIGGIPFKIISDERGFYNKYNQKKLHAAAKRMNEGKYIV
HDIVE
Download Length: 258 bp
>AT167101 NZ_CP074680:1856417-1856668 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA