Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2002308..2002579 Replicon chromosome
Accession NZ_CP058656
Organism Escherichia coli strain WCHEC035125

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2002438..2002541 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2002308..2002579 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZR25_RS09625 1998863..1999525 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZR25_RS09630 1999549..2000205 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HZR25_RS09635 2000307..2000537 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZR25_RS09640 2000676..2001050 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HZR25_RS09645 2001054..2001926 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HZR25_RS09650 2001939..2002280 + 342 WP_000976492.1 YebY family protein -
- 2002308..2002579 - 272 - - Antitoxin
- 2002438..2002541 + 104 - - Toxin
HZR25_RS09655 2002676..2003332 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HZR25_RS09660 2003333..2003524 - 192 WP_001296140.1 YebW family protein -
HZR25_RS09665 2003629..2003865 - 237 WP_001295499.1 DUF1480 family protein -
HZR25_RS09670 2003983..2005422 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1948777..2005428 56651


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167032 NZ_CP058656:2002438-2002541 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167032 NZ_CP058656:c2002579-2002308 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References