Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2000354..2000625 Replicon chromosome
Accession NZ_CP058651
Organism Escherichia coli strain WCHEC035123

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2000484..2000587 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2000354..2000625 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZR24_RS09615 1996909..1997571 - 663 WP_000944256.1 exodeoxyribonuclease X -
HZR24_RS09620 1997595..1998251 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HZR24_RS09625 1998353..1998583 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HZR24_RS09630 1998722..1999096 + 375 WP_000204699.1 CopC domain-containing protein YobA -
HZR24_RS09635 1999100..1999972 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
HZR24_RS09640 1999985..2000326 + 342 WP_000976492.1 YebY family protein -
- 2000354..2000625 - 272 - - Antitoxin
- 2000484..2000587 + 104 - - Toxin
HZR24_RS09645 2000722..2001378 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HZR24_RS09650 2001379..2001570 - 192 WP_001296140.1 YebW family protein -
HZR24_RS09655 2001675..2001911 - 237 WP_001295499.1 DUF1480 family protein -
HZR24_RS09660 2002029..2003468 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T167000 NZ_CP058651:2000484-2000587 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT167000 NZ_CP058651:c2000625-2000354 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References