Detailed information of TA system TA166992

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 6575590..6576094
• Replicon: chromosome
• Accession: NZ_CP058644
• Organism: Pseudomonas yamanorum strain GZD14026

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HZF02_RS30515
• Protein ID: WP_179448438.1
• Coordinates: 6575590..6575865 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HZF02_RS30520
• Protein ID: WP_155583689.1
• Coordinates: 6575855..6576094 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HZF02_RS30500	6570830..6572671	+	1842	WP_179448437.1	dihydroxy-acid dehydratase	-
HZF02_RS30505	6572865..6573923	-	1059	WP_155583692.1	haloacid dehalogenase-like hydrolase	-
HZF02_RS30510	6574163..6575554	+	1392	WP_155583691.1	L-cystine transporter	-
HZF02_RS30515	6575590..6575865	-	276	WP_179448438.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HZF02_RS30520	6575855..6576094	-	240	WP_155583689.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
HZF02_RS30525	6576178..6576690	-	513	WP_179448439.1	dihydrofolate reductase	-
HZF02_RS30530	6576781..6578160	+	1380	WP_179448440.1	DUF2868 domain-containing protein	-
HZF02_RS30535	6578153..6579526	+	1374	WP_179448441.1	DUF3482 domain-containing protein	-
HZF02_RS30540	6579523..6580077	-	555	WP_179448442.1	HD domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-70)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10863.59 Da
• Isoelectric Point: 9.8424

>T166992 WP_179448438.1 NZ_CP058644:c6575865-6575590 [Pseudomonas yamanorum]
MTYSLEFDARALKEWHKLGDTVRQQFKKKLVELLSYPRIEANRLHGLPDCYKIKLRSSGYRLVYQVIDQEVTVFVVAVDK
RERDEVYRKVS

Nucleotide

• Length: 276 bp

>T166992 NZ_CP074580:c2252481-2251948 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTATTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8997.36 Da
• Isoelectric Point: 4.8096

>AT166992 WP_155583689.1 NZ_CP058644:c6576094-6575855 [Pseudomonas yamanorum]
MASINVRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEEDEALFATVRERLAAPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT166992 NZ_CP074580:c2252758-2252492 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA