Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/upstrm_HI1419-dnstrm_HI1420 |
Location | 806794..807390 | Replicon | chromosome |
Accession | NZ_CP058644 | ||
Organism | Pseudomonas yamanorum strain GZD14026 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | HZF02_RS03680 | Protein ID | WP_179448976.1 |
Coordinates | 807088..807390 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | HZF02_RS03675 | Protein ID | WP_155584892.1 |
Coordinates | 806794..807084 (-) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HZF02_RS03655 | 803160..805235 | - | 2076 | WP_179448973.1 | TonB-dependent copper receptor | - |
HZF02_RS03660 | 805328..805753 | - | 426 | WP_179448974.1 | DUF2946 domain-containing protein | - |
HZF02_RS03665 | 805775..806254 | - | 480 | WP_155584894.1 | copper chaperone PCu(A)C | - |
HZF02_RS03670 | 806301..806696 | - | 396 | WP_179448975.1 | DUF2946 domain-containing protein | - |
HZF02_RS03675 | 806794..807084 | - | 291 | WP_155584892.1 | putative addiction module antidote protein | Antitoxin |
HZF02_RS03680 | 807088..807390 | - | 303 | WP_179448976.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HZF02_RS03685 | 807637..808356 | - | 720 | WP_179448977.1 | cobalt-precorrin-6A reductase | - |
HZF02_RS03690 | 808353..809558 | - | 1206 | WP_179448978.1 | precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE | - |
HZF02_RS03695 | 809682..810962 | + | 1281 | WP_179450917.1 | precorrin-3B synthase | - |
HZF02_RS03700 | 810955..811581 | + | 627 | WP_155584888.1 | precorrin-8X methylmutase | - |
HZF02_RS03705 | 811581..812312 | + | 732 | WP_155584887.1 | precorrin-2 C(20)-methyltransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11559.42 Da Isoelectric Point: 9.8284
>T166984 WP_179448976.1 NZ_CP058644:c807390-807088 [Pseudomonas yamanorum]
MIDFDESIEFVRWLEALRDPLAKVRVLTRLRAAELGNFGDCEPVGHGACEMRIHYGSGYRVYFTRRDKVVYLLLIGGDKS
TQKRDIKRARQMAKNLGIKE
MIDFDESIEFVRWLEALRDPLAKVRVLTRLRAAELGNFGDCEPVGHGACEMRIHYGSGYRVYFTRRDKVVYLLLIGGDKS
TQKRDIKRARQMAKNLGIKE
Download Length: 303 bp
>T166984 NZ_CP074577:187061-187459 [Escherichia coli]
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTCACGATAAAGAACAAACCCGCCAGCGTCAGGGAGCGTTTTAA
CCTGAACCAGGGGAGAATGTGTATCAGTTCGGTCACCCTGATGGAGTTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCTGCCGCAGCCACACACAGC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCAG
TCGGGGACTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGACGGTCTGAGAATTGAAGACTGGAGCTGA
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTCACGATAAAGAACAAACCCGCCAGCGTCAGGGAGCGTTTTAA
CCTGAACCAGGGGAGAATGTGTATCAGTTCGGTCACCCTGATGGAGTTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCTGCCGCAGCCACACACAGC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCAG
TCGGGGACTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGACGGTCTGAGAATTGAAGACTGGAGCTGA
Antitoxin
Download Length: 97 a.a. Molecular weight: 10361.84 Da Isoelectric Point: 5.0491
>AT166984 WP_155584892.1 NZ_CP058644:c807084-806794 [Pseudomonas yamanorum]
MSESFTRFDAANYLKTPEDMAAYLDACFEEDAGDGLLIRTALNDIARAQGMTQVARNAGLGRESLYKALSSTGNPEFATI
MKVMKALGLKLHATAI
MSESFTRFDAANYLKTPEDMAAYLDACFEEDAGDGLLIRTALNDIARAQGMTQVARNAGLGRESLYKALSSTGNPEFATI
MKVMKALGLKLHATAI
Download Length: 291 bp
>AT166984 NZ_CP074577:186834-187061 [Escherichia coli]
ATGGAAACCACCGTATTTTTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTGTCGGACGAACCAGAATCATTACGCCAGCCGGAGAGACATGGGACGAATGGTTCGACGGAC
ACAACGTCAGCGCCGATTTTATGGATAACAGGGAACAGCCCGGCATGCAGGAAAGGGAGTCATTCTGA
ATGGAAACCACCGTATTTTTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTGTCGGACGAACCAGAATCATTACGCCAGCCGGAGAGACATGGGACGAATGGTTCGACGGAC
ACAACGTCAGCGCCGATTTTATGGATAACAGGGAACAGCCCGGCATGCAGGAAAGGGAGTCATTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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