Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2260958..2261226 Replicon chromosome
Accession NZ_CP058596
Organism Escherichia coli strain UPEC_U013

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2261086..2261188 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2260958..2261226 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYE75_RS10490 2257510..2258172 - 663 WP_000944256.1 exodeoxyribonuclease X -
HYE75_RS10495 2258196..2258852 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
HYE75_RS10500 2258955..2259185 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HYE75_RS10505 2259324..2259698 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HYE75_RS10510 2259702..2260574 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HYE75_RS10515 2260587..2260928 + 342 WP_000984819.1 YebY family protein -
- 2260958..2261226 - 269 - - Antitoxin
- 2261086..2261188 + 103 - - Toxin
HYE75_RS10520 2261323..2261979 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
HYE75_RS10525 2261980..2262171 - 192 WP_001317886.1 YebW family protein -
HYE75_RS10530 2262276..2262512 - 237 WP_001295499.1 DUF1480 family protein -
HYE75_RS10535 2262630..2264069 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166883 NZ_CP058596:2261086-2261188 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT166883 NZ_CP058596:c2261226-2260958 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References