Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2146907..2147178 Replicon chromosome
Accession NZ_CP058574
Organism Escherichia coli strain EC1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2147037..2147140 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2146907..2147178 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYH05_RS10225 2143462..2144124 - 663 WP_000944256.1 exodeoxyribonuclease X -
HYH05_RS10230 2144148..2144804 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
HYH05_RS10235 2144906..2145136 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HYH05_RS10240 2145275..2145649 + 375 WP_000204705.1 CopC domain-containing protein YobA -
HYH05_RS10245 2145653..2146525 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
HYH05_RS10250 2146538..2146879 + 342 WP_000976481.1 YebY family protein -
- 2146907..2147178 - 272 - - Antitoxin
- 2147037..2147140 + 104 - - Toxin
HYH05_RS10255 2147275..2147931 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
HYH05_RS10260 2147932..2148123 - 192 WP_001296140.1 YebW family protein -
HYH05_RS10265 2148228..2148464 - 237 WP_001295499.1 DUF1480 family protein -
HYH05_RS10270 2148582..2150021 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2123120..2163017 39897


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T166841 NZ_CP058574:2147037-2147140 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT166841 NZ_CP058574:c2147178-2146907 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References