166803

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 3146082..3146598 Replicon chromosome
Accession NZ_CP058561
Organism Vallitalea guaymasensis strain Ra1766G1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HYG85_RS13655 Protein ID WP_113673461.1
Coordinates 3146082..3146339 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HYG85_RS13660 Protein ID WP_113673462.1
Coordinates 3146341..3146598 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYG85_RS13640 (HYG85_13555) 3142080..3143588 + 1509 WP_212690131.1 L-arabinose isomerase -
HYG85_RS13645 (HYG85_13560) 3143628..3145304 + 1677 WP_212690132.1 ribulokinase -
HYG85_RS13650 (HYG85_13565) 3145306..3145998 + 693 WP_212690133.1 L-ribulose-5-phosphate 4-epimerase -
HYG85_RS13655 (HYG85_13570) 3146082..3146339 - 258 WP_113673461.1 Txe/YoeB family addiction module toxin Toxin
HYG85_RS13660 (HYG85_13575) 3146341..3146598 - 258 WP_113673462.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
HYG85_RS13665 (HYG85_13580) 3146841..3147737 - 897 WP_212690134.1 AraC family transcriptional regulator -
HYG85_RS13670 (HYG85_13585) 3147942..3149000 + 1059 WP_212690135.1 Gfo/Idh/MocA family oxidoreductase -
HYG85_RS13675 (HYG85_13590) 3149011..3149736 + 726 WP_244971194.1 ThuA domain-containing protein -
HYG85_RS13680 (HYG85_13595) 3150102..3150944 + 843 WP_113674098.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10143.67 Da        Isoelectric Point: 9.4642

>T166803 WP_113673461.1 NZ_CP058561:c3146339-3146082 [Vallitalea guaymasensis]
MNKVFSDLAWQDYTSWLIEDKKILKRINTLLKDIDRNGNIGLGKPEPLRYNLRGYWSRRITDEHRLIYKIEDNEILIVAC
KGHNN

Download         Length: 258 bp

>T166803 NZ_CP074446:2609939-2610424 [Klebsiella aerogenes]
ATGGGAAAAATAAGTGCGCCTGCACCGCTATCTTCACACCATCAGATTGCGGAGTTTTGTTGTGGAGAAACGGTTCTCGA
TCAATGGCTAAAACAACGAGGAATGAAAAACCAGGCTCAGGGCGCCGCGAGAACCTTTGTGGTCTGCAAGGAAGATAGCC
ATCAGGTGGTGGGATTTTATTCGTTAGCAACCGGCAGCGTTAATCACTCGGAAGCCACTGGCGGCCTGCGGCGCAATATG
CCCGATCCTATCCCGGTCATCATTCTCGCCCGCCTGGCGATCGACTGCGCGTTTCACGGACAGGGGCTGGGAGCTGATTT
ACTCCATGATGCGCTCTTACGCAGTTATCGCGTTGCCGAAAATGTTGGCGTACGTGCCCTGATGGTCCATGCCCTGACCG
ATAGCGCGAAGCGATTCTATTTACACCACGGATTCAAAGCCTCCACCACCCAGGAACGCACACTTTTCCTCGCGTTGCCT
AAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9877.29 Da        Isoelectric Point: 7.1631

>AT166803 WP_113673462.1 NZ_CP058561:c3146598-3146341 [Vallitalea guaymasensis]
MIATNYSNARQKFKEYCDIANDDFETIIVTRKNGGNVVMMSETEYNNLLENIFVMGNKTNYEHIMKSIDQLKKGHAKKKN
LIEVE

Download         Length: 258 bp

>AT166803 NZ_CP074446:2609685-2609951 [Klebsiella aerogenes]
ATGAAATCAGATATCCAACTCAACATCCGGGCGAAGGAGTCCCAGCGGGCGCTGATTGATGCGGCTGCCGAAATTCTGCA
CAAATCGCGGACCGACTTTATCCTTGAGATGGCCTGCCAGGCGGCAGAAAACGTCATTCTCGACCGTCGGGTGTTTAACT
TAAGCGATGAGCAATACGCCGAATTTATCGACATGCTGGATGCGCCGGTTGAAGCTAACCCCGCTCTCGATAAATTGCTG
GCGAGAAAACCGCAATGGGAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References