Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2489250..2489395 Replicon chromosome
Accession NZ_CP058544
Organism Klebsiella pneumoniae strain S161-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2489286..2489388 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2489250..2489395 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYH18_RS12045 2484380..2486440 + 2061 WP_004151449.1 oligopeptidase B -
HYH18_RS12050 2486444..2487103 - 660 WP_002911407.1 exodeoxyribonuclease X -
HYH18_RS12055 2487182..2487412 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HYH18_RS12060 2487525..2487899 + 375 WP_039819395.1 CopC domain-containing protein YobA -
HYH18_RS12065 2487903..2488772 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HYH18_RS12070 2488789..2489127 + 339 WP_002911404.1 YebY family protein -
- 2489250..2489395 - 146 - - Antitoxin
- 2489286..2489388 + 103 - - Toxin
HYH18_RS12075 2489764..2489907 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HYH18_RS12080 2490012..2490980 - 969 WP_004151446.1 VirK/YbjX family protein -
HYH18_RS12085 2491137..2491790 + 654 WP_094310679.1 protein-serine/threonine phosphatase -
HYH18_RS12090 2491787..2491978 - 192 WP_002911395.1 YebW family protein -
HYH18_RS12095 2492076..2492315 - 240 WP_002911393.1 YebV family protein -
HYH18_RS12100 2492431..2493864 - 1434 WP_094310678.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166759 NZ_CP058544:2489286-2489388 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT166759 NZ_CP058544:c2489395-2489250 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References