Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 480179..480759 Replicon plasmid pAtEML4
Accession NZ_CP058527
Organism Agrobacterium tumefaciens strain EML4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EML4_RS25975 Protein ID WP_121593637.1
Coordinates 480376..480759 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EML4_RS25970 Protein ID WP_080868762.1
Coordinates 480179..480379 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EML4_RS25955 476000..476641 + 642 WP_162993132.1 helix-turn-helix domain-containing protein -
EML4_RS25960 476740..478938 - 2199 WP_121593635.1 EAL domain-containing protein -
EML4_RS25965 479661..479987 - 327 WP_121593636.1 transposase -
EML4_RS25970 480179..480379 + 201 WP_080868762.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
EML4_RS25975 480376..480759 + 384 WP_121593637.1 type II toxin-antitoxin system VapC family toxin Toxin
EML4_RS25980 481099..481304 - 206 Protein_494 aldo/keto reductase -
EML4_RS25985 481666..482004 + 339 Protein_495 helix-turn-helix transcriptional regulator -
EML4_RS25990 482122..482445 + 324 WP_162993137.1 hypothetical protein -
EML4_RS25995 482553..483404 - 852 WP_121593638.1 2-hydroxy-3-oxopropionate reductase -
EML4_RS26000 483408..484193 - 786 WP_060724635.1 hydroxypyruvate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..520191 520191


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-116)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 16424.30 Da        Isoelectric Point: 12.9037

>T166749 WP_121593637.1 NZ_CP058527:480376-480759 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 384 bp

>T166749 NZ_CP074425:3411535-3411753 [Salmonella sp. SJTUF15034]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 8605.68 Da        Isoelectric Point: 12.6195

>AT166749 WP_080868762.1 NZ_CP058527:480179-480379 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 201 bp

>AT166749 NZ_CP074425:3411133-3411507 [Salmonella sp. SJTUF15034]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References