Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 3608283..3608785 Replicon chromosome
Accession NZ_CP058409
Organism Trichlorobacter lovleyi strain IAE

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FY034_RS16670 Protein ID WP_265552565.1
Coordinates 3608531..3608785 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FY034_RS16665 Protein ID WP_265552564.1
Coordinates 3608283..3608534 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY034_RS16645 (FY034_16650) 3603352..3605361 - 2010 WP_265552556.1 molybdopterin-dependent oxidoreductase -
FY034_RS16650 (FY034_16655) 3605481..3606470 + 990 WP_265552558.1 ADP-glyceromanno-heptose 6-epimerase -
FY034_RS16655 (FY034_16660) 3606497..3607123 + 627 WP_265552560.1 hypothetical protein -
FY034_RS16660 (FY034_16665) 3607209..3608156 - 948 WP_265552562.1 adenosylcobinamide-phosphate synthase CbiB -
FY034_RS16665 (FY034_16670) 3608283..3608534 + 252 WP_265552564.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FY034_RS16670 (FY034_16675) 3608531..3608785 + 255 WP_265552565.1 Txe/YoeB family addiction module toxin Toxin
FY034_RS16675 (FY034_16680) 3609239..3610915 + 1677 WP_265552568.1 DUF1566 domain-containing protein -
FY034_RS16680 (FY034_16685) 3611048..3611635 - 588 WP_265552570.1 DUF1643 domain-containing protein -
FY034_RS16685 (FY034_16690) 3611719..3613014 - 1296 WP_265552572.1 HipA domain-containing protein -
FY034_RS16690 (FY034_16695) 3613011..3613268 - 258 WP_265552574.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3456232..3630935 174703


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9956.52 Da        Isoelectric Point: 8.4984

>T166742 WP_265552565.1 NZ_CP058409:3608531-3608785 [Trichlorobacter lovleyi]
MMIKFSTAAWEDYLYWQTTDKAMLKRINQLIRDIQREPFAGIGKPEPLKHQLAGFWSRRIDSCHRLVYAVEGDTLLIAQC
RDHY

Download         Length: 255 bp

>T166742 NZ_CP074425:310524-310892 [Salmonella sp. SJTUF15034]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGTCGTTCGCTTACGCGCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9387.61 Da        Isoelectric Point: 5.5900

>AT166742 WP_265552564.1 NZ_CP058409:3608283-3608534 [Trichlorobacter lovleyi]
MNALTYTYTRQHFAEVMKSVNEDHVPVVVTSQRGKPVVILSLDDFHAYEETAYLLRNPQGAKRLLESVEELRAGGGQVRD
LVE

Download         Length: 252 bp

>AT166742 NZ_CP074425:310306-310527 [Salmonella sp. SJTUF15034]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGCGCGGTGACGGCGGGCCCTGTCAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGGAGCTGGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References