Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 412707..413292 Replicon chromosome
Accession NZ_CP058364
Organism Galbibacter sp. BG1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag HX109_RS01800 Protein ID WP_178949512.1
Coordinates 412707..413006 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HX109_RS01805 Protein ID WP_178949513.1
Coordinates 413008..413292 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HX109_RS01780 408433..409179 + 747 WP_178949509.1 alpha/beta fold hydrolase -
HX109_RS01785 409435..411164 + 1730 Protein_350 amidohydrolase -
HX109_RS01790 411332..411724 + 393 WP_178949510.1 VOC family protein -
HX109_RS01795 411874..412548 + 675 WP_178949511.1 haloacid dehalogenase type II -
HX109_RS01800 412707..413006 + 300 WP_178949512.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HX109_RS01805 413008..413292 + 285 WP_178949513.1 putative addiction module antidote protein Antitoxin
HX109_RS01810 413331..414872 - 1542 WP_178949514.1 replicative DNA helicase -
HX109_RS01815 415042..415995 - 954 WP_178949515.1 acetyl-CoA carboxylase carboxyltransferase subunit alpha -
HX109_RS01820 416043..416945 - 903 WP_178949516.1 DMT family transporter -
HX109_RS01825 416932..418011 - 1080 WP_178949517.1 LptF/LptG family permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Uncharacterized protein HI1420

(2-91)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11772.86 Da        Isoelectric Point: 10.4809

>T166738 WP_178949512.1 NZ_CP058364:412707-413006 [Galbibacter sp. BG1]
MYFIEKTVEFDKWIKKLKDFRAKSKILFRIQKLESDEHFGDCKSVGDGIREIRINFAKGYRVYFKEKDGKIIILLIGGNK
STQQKDIIKAKEIWRKLNS

Download         Length: 300 bp

>T166738 NZ_CP074415:c2183735-2183433 [Vibrio parahaemolyticus]
ATGGCTGAAGTAATCTGGACTGAACCAGCGTTATCTGACCTCAATGATATCGCTGAATACATCGCACTTGAAAATATCGT
AGCTGCAAAGCAGTTAGTACAAACGATCTTCTCCAAAGTCGAACGCCTACAAACTTTCCCAGAGTCAGGTCGTATTCCAC
CCGAGCTAGAACATTTAAGTTATCGTGAAGTTGTCGTTAATCCATGTCGTGTTTTCTATAAACAAGACGGTGACAAAGTG
TTTATTCTGTTTGTTATGCGTGCAGAGAGAGATTTGCGTAAGTTCTTGTTGGGTAAGCAATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10156.76 Da        Isoelectric Point: 7.0090

>AT166738 WP_178949513.1 NZ_CP058364:413008-413292 [Galbibacter sp. BG1]
MKTSKFDIADYLDNEEMIAEYLNTVLEEGNSNDLVVAIGHVAKAIGMTKIAEKTGMSRPSLYKALSDGNKPQFGTIVKVL
KAIGGQIQVKPTTV

Download         Length: 285 bp

>AT166738 NZ_CP074415:c2183980-2183723 [Vibrio parahaemolyticus]
ATGAAAGTAGAACTAGTTACATCACTCAAACGTCAAGCAACTAAGATCCTCGCCGATCTCCACGACACCAAAGAACCAGT
GTTAATTACCGAGCATGGTAAGCCATCTGCGTATCTAGTTGATGTTGATGACTACGAATTTATGCAAAATCGTTTAGCTA
TTCTTGAGGGTATTGCACGAGGTGAGCGTGCACTAGCTGATGGTAAAGTTGTAAGCCATGATGAAGCCAAGGACAAAATG
TCAAAATGGCTGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References