Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1908073..1908218 Replicon chromosome
Accession NZ_CP058361
Organism Klebsiella pneumoniae strain KP77

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1908109..1908211 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1908073..1908218 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HYD36_RS09160 1903203..1905263 + 2061 WP_004151449.1 oligopeptidase B -
HYD36_RS09165 1905267..1905926 - 660 WP_002911407.1 exodeoxyribonuclease X -
HYD36_RS09170 1906005..1906235 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HYD36_RS09175 1906348..1906722 + 375 WP_023286640.1 CopC domain-containing protein YobA -
HYD36_RS09180 1906726..1907595 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
HYD36_RS09185 1907612..1907950 + 339 WP_016529031.1 YebY family protein -
- 1908073..1908218 - 146 - - Antitoxin
- 1908109..1908211 + 103 - - Toxin
HYD36_RS09190 1908585..1908728 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HYD36_RS09195 1908833..1909801 - 969 WP_074194451.1 VirK/YbjX family protein -
HYD36_RS09200 1909958..1910611 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
HYD36_RS09205 1910608..1910799 - 192 WP_002911395.1 YebW family protein -
HYD36_RS09210 1910897..1911136 - 240 WP_002911393.1 YebV family protein -
HYD36_RS09215 1911252..1912685 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166722 NZ_CP058361:1908109-1908211 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT166722 NZ_CP058361:c1908218-1908073 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References