Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1990686..1990831 | Replicon | chromosome |
| Accession | NZ_CP058358 | ||
| Organism | Klebsiella pneumoniae strain KP486 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1990722..1990824 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1990686..1990831 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HYD35_RS09615 | 1985816..1987876 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| HYD35_RS09620 | 1987880..1988539 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| HYD35_RS09625 | 1988618..1988848 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| HYD35_RS09630 | 1988961..1989335 | + | 375 | WP_023286640.1 | CopC domain-containing protein YobA | - |
| HYD35_RS09635 | 1989339..1990208 | + | 870 | WP_023286639.1 | copper homeostasis membrane protein CopD | - |
| HYD35_RS09640 | 1990225..1990563 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 1990686..1990831 | - | 146 | - | - | Antitoxin |
| - | 1990722..1990824 | + | 103 | - | - | Toxin |
| HYD35_RS09645 | 1991198..1991341 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| HYD35_RS09650 | 1991446..1992414 | - | 969 | WP_074194451.1 | VirK/YbjX family protein | - |
| HYD35_RS09655 | 1992571..1993224 | + | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| HYD35_RS09660 | 1993221..1993412 | - | 192 | WP_002911395.1 | YebW family protein | - |
| HYD35_RS09665 | 1993510..1993749 | - | 240 | WP_002911393.1 | YebV family protein | - |
| HYD35_RS09670 | 1993865..1995298 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T166703 NZ_CP058358:1990722-1990824 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT166703 NZ_CP058358:c1990831-1990686 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
